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作者 |
Liu, YW; Cheng, YB; Liaw, CC; Chen, CH; Guh, JH; Hwang, TL; Tsai, JS; Wang, WB; Shen, YC |
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[摘要]：Investigation of the leaves and twigs of Callicarpa longissima resulted in the isolation of four new compounds (14), callilongisins A-D, and five known compounds, ursolic acid, 3-oxoanticopalic acid, (E)-6 beta-hydroxylabda-8(17),13-dien-15-oic acid, 5-hydroxy-3,6,7,4'-tetramethoxyflavone, and artemetin. Compounds 1-3 are 3,4-seco-abietane-type diterpenoids, and compound 4 is an analogue of a labdenoic-type diterpene. The structure of compound 1 was confirmed by X-ray crystallographic analysis. Cytotoxicity against a human prostate cancer cell line (PC3) and anti-inflammatory activities of the isolated compounds were evaluated. |
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