[摘要]：The first total synthesis of the Leucetta alkaloid calcaridine A (I) is described based on a biosynthetic postulate. Application of an oxidative rearrangement of a 4,5-disubstituted imidazole leads to the formation of both calcaridine A and epi-calcaridine A. An X-ray crystal structure detn. on the latter has allowed the assignment of the relative configuration of the epimeric natural product and calcaridine A by extrapolation.
