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Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study

  作者 CHAE PIL SEOK; RANA ROHINI R; GOTFRYD KAMIL; RASMUSSEN SOREN G F; KRUSE ANDREW C; CHO KYUNG HO; CAPALDI STEFANO; CARLSSON EMIL; KOBILKA BRIAN; LOLAND CLAUS J; GETHER ULRIK; BANERJEE SURAJIT; BYRNE BERNADETTE; LEE JOHN K; GELLMAN SAMUEL H  
  选自 期刊  Chemical Communications;  卷期  2013年49-23;  页码  2287-2289  
  关联知识点  
 

[摘要]The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

 
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