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Chromogenic and Fluorogenic Sensing of Biological Thiols in Aqueous Solutions Using BODIPY-Based Reagents

  作者 ISIK MURAT; OZDEMIR TUGBA; TURAN IIKE SIMSEK; KOLEMEN SAFACAN; AKKAYA ENGIN U  
  选自 期刊  Organic Letters;  卷期  2013年15-1;  页码  216-219  
  关联知识点  
 

[摘要]Judicious design of BODIPY dyes carrying nitroethenyl substituents in conjugation with the BODIPY core yields dyes that respond to biological thiols by both absorbance and emission changes. Incorporation of solubilizing ethyleneglycol units ensures water solubility. The result is bright signaling of biologically relevant thiols in the longer wavelength region of the visible spectrum and in aqueous solutions.

 
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