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A New Non-Cross-Linked Polystyrene Supported 2-Phenylimino-2-oxazolidine Chiral Auxiliary: Synthesis and Application in Asymmetric Alkylation Reactions

  作者 HU FUQIANG; XIA DEXIN; LU CUIFEN; CHEN ZUXING; YANG GUICHUN  
  选自 期刊  European Journal of Organic Chemistry;  卷期  2010年-29;  页码  5552-5554  
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[摘要]The synthesis of novel non-cross-linked polystyrene supported 2-phenylimino-2-oxazolidine is described, and its use as a chiral auxiliary in asymmetric alkylation reactions is demonstrated by the synthesis of several chiral amides (>96 % ee), Furthermore, recovery and recycling of the polymer-supported chiral auxiliary were successfully achieved without appreciable reduction in the yield or stereoselectivity.

 
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