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Asymmetric direct aldol reactions of pyruvic derivatives.

  作者 Luo, Sanzhong;Xu, Hui;Chen, Liujuan;Cheng, Jin-Pei;  
  选自 期刊  Organic Letters;  卷期  2008年10-9;  页码  1775-1778  
  关联知识点  
 

[摘要]as I/TfOH, can effectively catalyze the direct aldol reactions of pyruvic derivs. with aldehydes. The reaction proceeded with excellent syn diastereoselectivities and enantioselectivities, thus functionally mimicking the pyruvate-dependent type I aldolases.

 
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