Synthesis and activity evaluation of 3'-floxuridinyl 4-[3-(3, 5-di-t-butyl-4-methoxyphenyl)-3-oxo-propenyl]benzoate: in vitro and in vivo as a potential dual-acting antitumor prodrug

[摘要]：BOBA (4-[3-(3, 5-di-tert-butyl-4-methoxyphenyl)-3-oxo-propenyl]benzoic acid), a substituted chalcone derivative, exhibits an excellent inducing differentiation on neoplastic cellular differentiation. FUDR (5-fluoro-2'-deoxyuridine, floxuridine) inhibits D

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