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Imidazo[1,2-a] pyrazines as novel PI3K inhibitors

作者	Gonzalez, SM; Hernandez, AI; Varela, C; Rodriguez-Aristegui, S; Alvarez, RM; Garcia, AB; Lorenzo, M; Rivero, V; Oyarzabal, J; Rabal, O; Bischoff, JR; Albarran, M; Cebria, A; Alfonso, P; Link, W; Fominaya, J; Pastor, J

选自	期刊 Bioorganic & Medicinal Chemistry Letters; 卷期 2012年22-5; 页码 1874-1878

关联知识点

[摘要]：Phosphoinositide-3-kinase (PI3K) is an important target for cancer therapeutics due to the deregulation of its signaling pathway in a wide variety of human cancers. We describe herein a novel series of imidazo[1,2-a]pyrazines as PI3K inhibitors. (c) 2012 Elsevier Ltd. All rights reserved.
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