[摘要]：An efficient arylation in water of tyrosine and phenylalanine side chains from unprotected iodopeptides is accomplished by using Suzuki-Miyaura cross-coupling processes. The method is compatible with the hydrophilic and thermolabile nature of biol. active peptides. Also of interest, the arylated tyrosine peptides can be accessed in one-pot mode starting from native peptides.
