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2,5,6-Trisubstituted N-Methylindoles from Site-Selective Suzuki-Miyaura Cross-Coupling, Twofold Heck and 6 pi-Electrocyclization-Dehydrogenation Reactions of 2,3,5-Tribromo-N-methylpyrrole

  作者 TOGUEM SERGEMITHERAND TENGHO; LANGER PETER  
  选自 期刊  SYNLETT;  卷期  2011年-4;  页码  513-516  
  关联知识点  
 

[摘要]Site-selective Suzuki-Miyaura reactions of 2,3,5-tribromo-N-methylpyrrole afforded 5-aryl-2,3-dibromo-N-methylpyrroles. These products were transformed into 2,5,6-trisubstituted N-methylindoles by twofold Heck reactions and subsequent 6 pi-electrocyclization- dehydrogenation reactions.

 
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