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A Concise Synthesis of Natural Benzofuran Neolignans and Analogues

  作者 DUAN XINFANG; SHEN GANG; ZHANG ZHANBIN  
  选自 期刊  Synthesis;  卷期  2010年-15;  页码  2547-2552  
  关联知识点  
 

[摘要]The first total synthesis of four naturally occurring benzofuran neolignans and two analogues was achieved in four steps in 44-51% overall yield. Key steps involved a two-step construction of benzofuran nucleus and a Suzuki coupling. This synthesis has been proven straightforward and efficient, and more related analogues can be prepared for structure-activity relationship explorations.

 
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