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A Concise Synthesis of 6-Amino-6-deoxy-DNJ and 6-Amino-1,6-dideoxy-L-talonojirimycin

  作者 TAMAYO JUAN A; FRANCO FRANCISCO; LO RE DANIELE  
  选自 期刊  SYNLETT;  卷期  2010年-9;  页码  1323-1326  
  关联知识点  
 

[摘要]A concise and straightforward synthesis of two amino-DNJ derivatives, 6-amino-6-deoxy-DNJ and 6-amino-1,6-dideoxy-L-talonojirimycin is described from a commercial and cheap starting material. The methodology employed takes advantage of dia-stereoselective reductive amination to achieve the two non-natural iminosugars in three and five steps, respectively.

 
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