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Preparation of N,N-Dimethyl Aromatic Amides from Aromatic Aldehydes with Dimethylamine and Iodine Reagents

  作者 BABA HARUKA; MORIYAMA KATSUHIKO; TOGO HIDEO  
  选自 期刊  SYNLETT;  卷期  2012年-8;  页码  1175-1180  
  关联知识点  
 

[摘要]Various N,N-dimethyl aromatic amides were obtained in good to moderate yields by the reaction of aromatic aldehydes with aqueous dimethylamine in the presence of molecular iodine or 1,3-diiodo-5,5-dimethylhydantoin (DIH) at room temperature. Under the same conditions and using the same procedure, treatment of aromatic aldehydes and morpholine in the presence of DIH also provided the corresponding N-aroyl morpholines in good to moderate yields.

 
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