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A Practical and Highly Efficient Hydroacylation Reaction of Azodicarboxylates with Aldehydes in Water

  作者 ZHANG QIANYING; PARKER ERICA; HEADLEY ALLAN D; NI BUKUO  
  选自 期刊  SYNLETT;  卷期  2010年-16;  页码  2453-2456  
  关联知识点  
 

[摘要]The very efficient hydroacylation reaction of azodicarboxylates, with various aldehydes, was carried successfully out at room temperature in water without the use of a catalyst to obtain a variety of hydrazine imide products in high yields. A wide range of aldehydes, including aliphatic and aromatic compounds, was considered, and the reaction is believed to proceed via a radical mechanism, in which water plays an integral role in stabilizing the radical intermediate.

 
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