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FACILE ONE-POT PROCEDURE FOR THE SYNTHESIS OF 2-AMINOTHIAZOLE DERIVATIVES

  作者 YIN GUODONG; MA JUNRUI; SHI HOUQIANG; TAO QING  
  选自 期刊  Heterocycles;  卷期  2012年85-8;  页码  1941-1948  
  关联知识点  
 

[摘要]A facile, efficient synthesis of 2-aminothiazole derivatives by the reaction of easily available aromatic methyl ketones with thiourea/N-substituted thioureas in the presence of copper(II) bromide was developed. The reaction underwent a one-pot alpha-bromination/cyclization process.

 
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