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Asymmetric Synthesis of 2,3-Dihydro-4-pyranones by Reaction of Chiral 3-Alkoxycyclobutanone and Aldehydes

  作者 NEGISHI SHOKO; ISHIBASHI HIROYUKI; MATSUO JUNICHI  
  选自 期刊  Organic Letters;  卷期  2010年12-21;  页码  4984-4987  
  关联知识点  
 

[摘要]Chiral cyclobutanone which had ethyl L-lactate as a chiral auxiliary at the 3-position reacted with aldehydes to give 2,3-dihydro-4-pyranones in up to 93% ee by combined use of titanium(IV) chloride and tin(II) chloride.

 
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