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Copper-Catalyzed Multicomponent Reaction: Synthesis of 4-Arylsulfonylimino-4,5-dihydrofuran Derivatives

  作者 SHANG YONGJIA; JU KAI; HE XINWEI; HU JINSONG; YU SHUYAN; ZHANG MIN; LIAO KAISHENG; WANG LIFEN; ZHANG PING  
  选自 期刊  Journal of Organic Chemistry;  卷期  2010年75-16;  页码  5743-5745  
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[摘要]A series of 4-arylsulfonylimino-4,5-dihydrolurans (14 examples) were efficiently synthesized in good to excellent yields by using the copper-catalyzed three-component reaction between sulfonyl azides, phenylacetylene, and beta-ketoesters in tetrahydrofuran (THF) at 40 degrees C for 8 h in the presence of triethylamine (TEA). A plausible mechanism for this process is proposed.

 
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