A concise route toward the formal synthesis of (+/-)-cephalotaxine has been developed. An intermolecular Pauson-Khand reaction was adopted to construct the cyclopentenone ring efficiently with high regioselectivity.
An enantioselective tandem Friedel-Crafts alkylation/Michael addition reaction of 1-methylindoles with nitroolefin enoates catalyzed by a chiral tridentate bisoxazoline-Zn(II) complex has been described. This method prov...
A new and efficient synthetic approach to [gem-bis(alkylthio)vinyl]allenes has been developed involving iron(III)-catalyzed dehydration C(sp(2))-C(sp(2)) coupling of tertiary propargyl alcohols and alpha-oxo ketene dithi...