The reactivity of N-benzyl- and N-cyclohexyl-2-benzoyl-3-phenylaziridines toward allenoates in supercritical carbon dioxide (scCO(2)) is described. The study led to the development of a sustainable and selective approach...
An efficient and convenient method was developed for the synthesis of novel 1,4-oxazepine- and 1,5-oxazocine-based sugar hybrids from readily available deoxysugar azides by means of tributylphosphine-mediated tandem reac...
The Pd(OAc)(2)/dppb system was found to be an efficient catalyst for the direct arylation of 3-substituted thiophene derivatives. The regioselectivity of the arylation strongly depends on the thiophene substituent and al...
A new method for the synthesis of pyrrolo[1,2-d][1,4]benzodiazepines is described. The method is based on the acid-catalyzed recyclization of N-[2-(5-alkyl-2-furyl)phenyl]-2-aminoacetamides and permits the formation of b...
alpha-Azido carbonyl compounds bearing a 2-alkenylaryl moiety in the a-position are found to be promising precursors in the synthesis of isoindoles via 1,3-dipolar cycloaddition of azides to alkenes. Applications of thes...
A series of sugar-fused spiro-pyrrolidine, -pyrrolizidine, and -indolizidine heterocycles were synthesized through a unique application of a 1,3-dipolar cycloaddition reaction of an azomethine ylide with a carbohydrate-d...