- Modular Evolution and the Origins of Symmetry: Reconstruction of a Three-Fold Symmetric Globular Protein
[作者:Broom, A; Doxey, AC; Lobsanov, YD; Berthin, LG; Rose, DR; Howell, PL; McConkey, BJ; Meiering, EM,期刊:Structure, 页码:161-171 , 文章类型: Article,,卷期:2012年20-1]
- The high frequency of internal structural symmetry in common protein folds is presumed to reflect their evolutionary origins from the repetition and fusion of ancient peptide modules, but little is known about the primar...
- Assembly of the Eukaryotic PLP-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme
[作者:Guedez, G; Hipp, K; Windeisen, V; Derrer, B; Gengenbacher, M; Bottcher, B; Sinning, I; Kappes, B; Tews, I,期刊:Structure, 页码:172-184 , 文章类型: Article,,卷期:2012年20-1]
- Biosynthesis of vitamins is fundamental to malaria parasites. Plasmodia synthesize the active form of vitamin B(6) (pyridoxal 5'-phosphate, PLP) using a PLP synthase complex. The EM analysis shown here reveals a random a...
- Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin
[作者:Du, JM; Kelly, AE; Funabiki, H; Patel, DJ,期刊:Structure, 页码:185-195 , 文章类型: Article,,卷期:2012年20-1]
- Survivin is an inhibitor of apoptosis family protein implicated in apoptosis and mitosis. In apoptosis, it has been shown to recognize the Smac/DIABLO protein. It is also a component of the chromosomal passenger complex,...
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