- Human Dedifferentiated Adipocytes Show Similar Properties to Bone Marrow-Derived Mesenchymal Stem Cells
[作者:Poloni, A; Maurizi, G; Leoni, P; Serrani, F; Mancini, S; Frontini, A; Zingaretti, MC; Siquini, W; Sarzani, R; Cinti, S,期刊:Stem Cells, 页码:965-974 , 文章类型: Article,,卷期:2012年30-5]
- Mature adipocytes are generally considered terminally differentiated because they have lost their proliferative abilities. Here, we studied the gene expression and functional properties of mature adipocytes isolated from...
- Atmospheric Oxygen Inhibits Growth and Differentiation of Marrow-Derived Mouse Mesenchymal Stem Cells via a p53-Dependent Mechanism: Implications for Long-Term Culture Expansion
[作者:Boregowda, SV; Krishnappa, V; Chambers, JW; Lograsso, PV; Lai, WT; Ortiz, LA; Phinney, DG,期刊:Stem Cells, 页码:975-987 , 文章类型: Article,,卷期:2012年30-5]
- Large scale expansion of human mesenchymal stem cells (MSCs) is routinely performed for clinical therapy. In contrast, developing protocols for large scale expansion of primary mouse MSCs has been more difficult due to u...
- Contribution of Hepatic Lineage Stage-Specific Donor Memory to the Differential Potential of Induced Mouse Pluripotent Stem Cells
[作者:Lee, SB; Seo, D; Choi, D; Park, KY; Holczbauer, A; Marquardt, JU; Conner, EA; Factor, VM; Thorgeirsson, SS,期刊:Stem Cells, 页码:997-1007 , 文章类型: Article,,卷期:2012年30-5]
- Recent studies suggested that induced pluripotent stem cells (iPSCs) retain a residual donor cell gene expression, which may impact their capacity to differentiate into cell of origin. Here, we addressed a contribution o...
- Identification and Regulation of a Stage-Specific Stem Cell Niche Enriched by Nanog-Positive Spermatogonial Stem Cells in the Mouse Testis
[作者:Ventea, S; Makela, JA; Kulmala, J; Westermarck, J; Toppari, J,期刊:Stem Cells, 页码:1008-1020 , 文章类型: Article,,卷期:2012年30-5]
- The ability of spermatogonial stem cells to acquire embryonic stem cell (ESC) properties in vitro has recently been of great interest. However, studies focused on the in vivo regulation of testicular stem cells have been...
- Tumor Tropism of Intravenously Injected Human-Induced Pluripotent Stem Cell-Derived Neural Stem Cells and Their Gene Therapy Application in a Metastatic Breast Cancer Model
[作者:Yang, J; Lam, DH; Goh, SS; Lee, EX; Zhao, Y; Tay, FC; Chen, C; Du, SH; Balasundaram, G; Shahbazi, M; Tham, CK; Ng, WH; Toh, HC; Wang, S,期刊:Stem Cells, 页码:1021-1029 , 文章类型: Article,,卷期:2012年30-5]
- Human pluripotent stem cells can serve as an accessible and reliable source for the generation of functional human cells for medical therapies. In this study, we used a conventional lentiviral transduction method to deri...
- Adipose Tissue-Derived Mesenchymal Stem Cells Improve Revascularization Outcomes to Restore Renal Function in Swine Atherosclerotic Renal Artery Stenosis
[作者:Eirin, A; Zhu, XY; Krier, JD; Tang, H; Jordan, KL; Grande, JP; Lerman, A; Textor, SC; Lerman, LO,期刊:Stem Cells, 页码:1030-1041 , 文章类型: Article,,卷期:2012年30-5]
- Reno-protective strategies are needed to improve renal outcomes in patients with atherosclerotic renal artery stenosis (ARAS). Adipose tissue-derived mesenchymal stem cells (MSCs) can promote renal regeneration, but thei...
- Interferon Gamma Inhibits Adipogenesis In Vitro and Prevents Marrow Fat Infiltration in Oophorectomized Mice
[作者:Vidal, C; Bermeo, S; Li, W; Huang, D; Kremer, R; Duque, G,期刊:Stem Cells, 页码:1042-1048 , 文章类型: Article,,卷期:2012年30-5]
- Interferon gamma (IFN?) has been reported to induce osteoblastogenesis from mesenchymal stem cells (MSCs) both in vitro and in vivo. With ageing, adipocytes outnumber osteoblasts within the bone microenvironment leading ...
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