- The Influence of Late Quaternary Climate-Change Velocity on Species Endemism
[作者：Sandel, B; Arge, L; Dalsgaard, B; Davies, RG; Gaston, KJ; Sutherland, WJ; Svenning, JC,期刊：Science, 页码：660-664 , 文章类型： Article，,卷期：2011年334-6056]
- The effects of climate change on biodiversity should depend in part on climate displacement rate (climate-change velocity) and its interaction with species' capacity to migrate. We estimated Late Quaternary glacial-inter...
- Long-Term Change in the Nitrogen Cycle of Tropical Forests
[作者：Hietz, P; Turner, BL; Wanek, W; Richter, A; Nock, CA; Wright, SJ,期刊：Science, 页码：664-666 , 文章类型： Article，,卷期：2011年334-6056]
- Deposition of reactive nitrogen (N) from human activities has large effects on temperate forests where low natural N availability limits productivity but is not known to affect tropical forests where natural N availabili...
- Drosophila Microbiome Modulates Host Developmental and Metabolic Homeostasis via Insulin Signaling
[作者：Shin, SC; Kim, SH; You, H; Kim, B; Kim, AC; Lee, KA; Yoon, JH; Ryu, JH; Lee, WJ,期刊：Science, 页码：670-674 , 文章类型： Article，,卷期：2011年334-6056]
- The symbiotic microbiota profoundly affect many aspects of host physiology; however, the molecular mechanisms underlying host-microbe cross-talk are largely unknown. Here, we show that the pyrroloquinoline quinone-depend...
- N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex
[作者：Scott, DC; Monda, JK; Bennett, EJ; Harper, JW; Schulman, BA,期刊：Science, 页码：674-678 , 文章类型： Article，,卷期：2011年334-6056]
- Although many eukaryotic proteins are amino (N)-terminally acetylated, structural mechanisms by which N-terminal acetylation mediates protein interactions are largely unknown. Here, we found that N-terminal acetylation o...
- mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
[作者：Zoncu, R; Bar-Peled, L; Efeyan, A; Wang, SY; Sancak, Y; Sabatini, DM,期刊：Science, 页码：678-683 , 文章类型： Article，,卷期：2011年334-6056]
- The mTOR complex 1 (mTORC1) protein kinase is a master growth regulator that is stimulated by amino acids. Amino acids activate the Rag guanosine triphosphatases (GTPases), which promote the translocation of mTORC1 to th...
- RNAP II CTD Phosphorylated on Threonine-4 Is Required for Histone mRNA 3 ' End Processing
[作者：Hsin, JP; Sheth, A; Manley, JL,期刊：Science, 页码：683-686 , 文章类型： Article，,卷期：2011年334-6056]
- The RNA polymerase II (RNAP II) largest subunit contains a C-terminal domain (CTD) with up to 52 Tyr(1)-Ser(2)-Pro(3)-Thr(4)-Ser(5)-Pro(6)-Ser(7) consensus repeats. Serines 2, 5, and 7 are known to be phosphorylated, and...
- Drosophila CENH3 Is Sufficient for Centromere Formation
[作者：Mendiburo, MJ; Padeken, J; Fulop, S; Schepers, A; Heun, P,期刊：Science, 页码：686-690 , 文章类型： Article，,卷期：2011年334-6056]
- CENH3 is a centromere-specific histone H3 variant essential for kinetochore assembly. Despite its central role in centromere function, there has been no conclusive evidence supporting CENH3 as sufficient to determine cen...
- Exercise and Genetic Rescue of SCA1 via the Transcriptional Repressor Capicua
[作者：Fryer, JD; Yu, P; Kang, H; Mandel-Brehm, C; Carter, AN; Crespo-Barreto, J; Gao, Y; Flora, A; Shaw, C; Orr, HT; Zoghbi, HY,期刊：Science, 页码：690-693 , 文章类型： Article，,卷期：2011年334-6056]
- Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by expansion of a translated CAG repeat in Ataxin-1 (ATXN1). To determine the long-term effects of exercise, we implemented a mild exercise...
- Bidirectional Control of Social Hierarchy by Synaptic Efficacy in Medial Prefrontal Cortex
[作者：Wang, F; Zhu, J; Zhu, H; Zhang, Q; Lin, ZM; Hu, HL,期刊：Science, 页码：693-697 , 文章类型： Article，,卷期：2011年334-6056]
- Dominance hierarchy has a profound impact on animals' survival, health, and reproductive success, but its neural circuit mechanism is virtually unknown. We found that dominance ranking in mice is transitive, relatively s...
- Social Network Size Affects Neural Circuits in Macaques
[作者：Sallet, J; Mars, RB; Noonan, MP; Andersson, JL; O'Reilly, JX; Jbabdi, S; Croxson, PL; Jenkinson, M; Miller, KL; Rushworth, MFS,期刊：Science, 页码：697-700 , 文章类型： Article，,卷期：2011年334-6056]
- It has been suggested that variation in brain structure correlates with the sizes of individuals' social networks. Whether variation in social network size causes variation in brain structure, however, is unknown. To add...
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