- Formation of ArF from LPdAr(F): Catalytic Conversion of Aryl Triflates to Aryl Fluorides
[作者:Watson, DA; Su, MJ; Teverovskiy, G; Zhang, Y; Garcia-Fortanet, J; Kinzel, T; Buchwald, SL,期刊:Science, 页码:1661-1664 , 文章类型: Article,,卷期:2009年325-5948]
- Despite increasing pharmaceutical importance, fluorinated aromatic organic molecules remain difficult to synthesize. Present methods require either harsh reaction conditions or highly specialized reagents, making the pre...
- Evolution of a Novel Phenolic Pathway for Pollen Development
[作者:Matsuno, M; Compagnon, V; Schoch, GA; Schmitt, M; Debayle, D; Bassard, JE; Pollet, B; Hehn, A; Heintz, D; Ullmann, P; Lapierre, C; Bernier, F; Ehlting, J; Werck-Reichhart, D,期刊:Science, 页码:1688-1692 , 文章类型: Article,,卷期:2009年325-5948]
- Metabolic plasticity, which largely relies on the creation of new genes, is an essential feature of plant adaptation and speciation and has led to the evolution of large gene families. A typical example is provided by th...
- Creating Bacterial Strains from Genomes That Have Been Cloned and Engineered in Yeast
[作者:Lartigue, C; Vashee, S; Algire, MA; Chuang, RY; Benders, GA; Ma, L; Noskov, VN; Denisova, EA; Gibson, DG; Assad-Garcia, N; Alperovich, N; Thomas, DW; Merryman, C; Hutchison, CA; Smith, HO; Venter, JC; Glass, JI,期刊:Science, 页码:1693-1696 , 文章类型: Article,,卷期:2009年325-5948]
- We recently reported the chemical synthesis, assembly, and cloning of a bacterial genome in yeast. To produce a synthetic cell, the genome must be transferred from yeast to a receptive cytoplasm. Here we describe methods...
- Optimizing Influenza Vaccine Distribution
[作者:Medlock, J; Galvani, AP,期刊:Science, 页码:1705-1708 , 文章类型: Article,,卷期:2009年325-5948]
- The criteria to assess public health policies are fundamental to policy optimization. Using a model parametrized with survey-based contact data and mortality data from influenza pandemics, we determined optimal vaccine a...
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