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  • Optical Deconstruction of Parkinsonian Neural Circuitry
    [作者:Gradinaru, V; Mogri, M; Thompson, KR; Henderson, JM; Deisseroth, K,期刊:Science, 页码:354-359 , 文章类型: Article,,卷期:2009年324-5925]
  • Deep brain stimulation (DBS) is a therapeutic option for intractable neurological and psychiatric disorders, including Parkinson's disease and major depression. Because of the heterogeneity of brain tissues where electro...
  • Probing Interactions Between Ultracold Fermions
    [作者:Campbell, GK; Boyd, MM; Thomsen, JW; Martin, MJ; Blatt, S; Swallows, MD; Nicholson, TL; Fortier, T; Oates, CW; Diddams, SA; Lemke, ND; Naidon, P; Julienne, P; Ye, J; Ludlow, AD,期刊:Science, 页码:360-363 , 文章类型: Article,,卷期:2009年324-5925]
  • At ultracold temperatures, the Pauli exclusion principle suppresses collisions between identical fermions. This has motivated the development of atomic clocks with fermionic isotopes. However, by probing an optical clock...
  • A Ferroelectric Oxide Made Directly on Silicon
    [作者:Warusawithana, MP; Cen, C; Sleasman, CR; Woicik, JC; Li, YL; Kourkoutis, LF; Klug, JA; Li, H; Ryan, P; Wang, LP; Bedzyk, M; Muller, DA; Chen, LQ; Levy, J; Schlom, DG,期刊:Science, 页码:367-370 , 文章类型: Article,,卷期:2009年324-5925]
  • Metal oxide semiconductor field-effect transistors, formed using silicon dioxide and silicon, have undergone four decades of staggering technological advancement. With fundamental limits to this technology close at hand,...
  • Atlantic Forcing of Persistent Drought in West Africa
    [作者:Shanahan, TM; Overpeck, JT; Anchukaitis, KJ; Beck, JW; Cole, JE; Dettman, DL; Peck, JA; Scholz, CA; King, JW,期刊:Science, 页码:377-380 , 文章类型: Article,,卷期:2009年324-5925]
  • Although persistent drought in West Africa is well documented from the instrumental record and has been primarily attributed to changing Atlantic sea surface temperatures, little is known about the length, severity, and ...
  • Protection of C-elegans from Anoxia by HYL-2 Ceramide Synthase
    [作者:Menuz, V; Howell, KS; Gentina, S; Epstein, S; Riezman, I; Fornallaz-Mulhauser, M; Hengartner, MO; Gomez, M; Riezman, H; Martinou, JC,期刊:Science, 页码:381-384 , 文章类型: Article,,卷期:2009年324-5925]
  • Oxygen deprivation is rapidly deleterious for most organisms. However, Caenorhabditis elegans has developed the ability to survive anoxia for at least 48 hours. Mutations in the DAF-2/DAF-16 insulin-like signaling pathwa...
  • Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis
    [作者:Nishikimi, A; Fukuhara, H; Su, WJ; Hongu, T; Takasuga, S; Mihara, H; Cao, QH; Sanematsu, F; Kanai, M; Hasegawa, H; Tanaka, Y; Shibasaki, M; Kanaho, Y; Sasaki, T; Frohman, MA; Fukui, Y,期刊:Science, 页码:384-387 , 文章类型: Article,,卷期:2009年324-5925]
  • During chemotaxis, activation of the small guanosine triphosphatase Rac is spatially regulated to organize the extension of membrane protrusions in the direction of migration. In neutrophils, Rac activation is primarily ...