- A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection
[作者：Pollin, TI; Damcott, CM; Shen, HQ; Ott, SH; Shelton, J; Horenstein, RB; Post, W; McLenithan, JC; Bielak, LF; Peyser, PA; Mitchell, BD; Miller, M; O'Connell, JR; Shuldiner, AR,期刊：Science, 页码：1702-1705 , 文章类型： Article，,卷期：2008年322-5908]
- Apolipoprotein C-III ( apoC-III) inhibits triglyceride hydrolysis and has been implicated in coronary artery disease. Through a genome- wide association study, we have found that about 5% of the Lancaster Amish are heter...
- Regulation of Dendritic Cell Migration by CD74, the MHC Class II-Associated Invariant Chain
[作者：Faure-Andre, G; Vargas, P; Yuseff, MI; Heuze, M; Diaz, J; Lankar, D; Steri, V; Manry, J; Hugues, S; Vascotto, F; Boulanger, J; Raposo, G; Bono, MR; Rosemblatt, M; Piel, M; Lennon-Dumenil, AM,期刊：Science, 页码：1705-1710 , 文章类型： Article，,卷期：2008年322-5908]
- Dendritic cells ( DCs) sample peripheral tissues of the body in search of antigens to present to T cells. This requires two processes, antigen processing and cell motility, originally thought to occur independently. We f...
- A Role for the ESCRT System in Cell Division in Archaea
[作者：Samson, RY; Obita, T; Freund, SM; Williams, RL; Bell, SD,期刊：Science, 页码：1710-1713 , 文章类型： Article，,卷期：2008年322-5908]
- Archaea are prokaryotic organisms that lack endomembrane structures. However, a number of hyperthermophilic members of the Kingdom Crenarchaea, including members of the Sulfolobus genus, encode homologs of the eukaryotic...
- De Novo Formation of a Subnuclear Body
[作者：Kaiser, TE; Intine, RV; Dundr, M,期刊：Science, 页码：1713-1717 , 文章类型： Article，,卷期：2008年322-5908]
- The mammalian cell nucleus contains structurally stable functional compartments. We show here that one of them, the Cajal body ( CB), can be formed de novo. Immobilization on chromatin of both CB structural components, s...
- The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin
[作者：Nagano, T; Mitchell, JA; Sanz, LA; Pauler, FM; Ferguson-Smith, AC; Feil, R; Fraser, P,期刊：Science, 页码：1717-1720 , 文章类型： Article，,卷期：2008年322-5908]
- A number of large noncoding RNAs ( ncRNAs) epigenetically silence genes through unknown mechanisms. The Air ncRNA is imprinted-monoallelically expressed from the paternal allele. Air is required for allele- specific sile...
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