- Integrating ecosystem-service tradeoffs into land-use decisions
[作者:Goldstein, JH; Caldarone, G; Duarte, TK; Ennaanay, D; Hannahs, N; Mendoza, G; Polasky, S; Wolny, S; Daily, GC,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7565-7570 , 文章类型: Article,,卷期:2012年109-19]
- Recent high-profile efforts have called for integrating ecosystem-service values into important societal decisions, but there are few demonstrations of this approach in practice. We quantified ecosystem-service values to...
- RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex
[作者:Jia, HJ; Wang, XY; Anderson, JT; Jankowsky, E,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7292-7297 , 文章类型: Article,,卷期:2012年109-19]
- Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex, which contains the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p. TRAMP poly...
- Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets
[作者:Alfaro, JF; Gong, CX; Monroe, ME; Aldrich, JT; Clauss, TRW; Purvine, SO; Wang, ZH; Camp, DG; Shabanowitz, J; Stanley, P; Hart, GW; Hunt, DF; Yang, F; Smith, RD,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7280-7285 , 文章类型: Article,,卷期:2012年109-19]
- O-linked N-acetylglucosamine (O-GlcNAc) is a reversible posttranslational modification of Ser and Thr residues on cytosolic and nuclear proteins of higher eukaryotes catalyzed by O-GlcNAc transferase (OGT). O-GlcNAc has ...
- Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment
[作者:Home, P; Saha, B; Ray, S; Dutta, D; Gunewardena, S; Yoo, B; Pal, A; Vivian, JL; Larson, M; Petroff, M; Gallagher, PG; Schulz, VP; White, KL; Golos, TG; Behr, B; Paul, S,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7362-7367 , 文章类型: Article,,卷期:2012年109-19]
- In the preimplantation mouse embryo, TEAD4 is critical to establishing the trophectoderm (TE)-specific transcriptional program and segregating TE from the inner cell mass (ICM). However, TEAD4 is expressed in the TE and ...
- Amorfrutins are potent antidiabetic dietary natural products
[作者:Weidner, C; de Groot, JC; Prasad, A; Freiwald, A; Quedenau, C; Kliem, M; Witzke, A; Kodelja, V; Han, CT; Giegold, S; Baumann, M; Klebl, B; Siems, K; Muller-Kuhrt, L; Schurmann, A; Schuler, R; Pfeiffer, AFH; Schroeder, FC; Bussow, K; Sauer, S,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7257-7262 , 文章类型: Article,,卷期:2012年109-19]
- Given worldwide increases in the incidence of obesity and type 2 diabetes, new strategies for preventing and treating metabolic diseases are needed. The nuclear receptor PPAR. (peroxisome proliferator-activated receptor ...
- Facial expressions of emotion are not culturally universal
[作者:Jack, RE; Garrod, OGB; Yu, H; Caldara, R; Schyns, PG,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7241-7244 , 文章类型: Article,,卷期:2012年109-19]
- Since Darwin's seminal works, the universality of facial expressions of emotion has remained one of the longest standing debates in the biological and social sciences. Briefly stated, the universality hypothesis claims t...
- Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication
[作者:Parussini, F; Tang, Q; Moin, SM; Mital, J; Urban, S; Ward, GE,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7463-7468 , 文章类型: Article,,卷期:2012年109-19]
- Apical membrane antigen 1 (AMA1) is a conserved transmembrane adhesin of apicomplexan parasites that plays an important role in host-cell invasion. Toxoplasma gondii AMA1 (TgAMA1) is secreted onto the parasite surface an...
- Anabolic action of parathyroid hormone regulated by the beta(2)-adrenergic receptor
[作者:Hanyu, R; Wehbi, VL; Hayata, T; Moriya, S; Feinstein, TN; Ezura, Y; Nagao, M; Saita, Y; Hemmi, H; Notomi, T; Nakamoto, T; Schipani, E; Takeda, S; Kaneko, K; Kurosawa, H; Karsenty, G; Kronenberg, HM; Vilardaga, JP; Noda, M,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7433-7438 , 文章类型: Article,,卷期:2012年109-19]
- Parathyroid hormone (PTH), the major calcium-regulating hormone, and norepinephrine (NE), the principal neurotransmitter of sympathetic nerves, regulate bone remodeling by activating distinct cell-surface G protein-coupl...
- Crystal structure of a Trypanosoma brucei metacaspase
[作者:McLuskey, K; Rudolf, J; Proto, WR; Isaacs, NW; Coombs, GH; Moss, CX; Mottram, JC,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7469-7474 , 文章类型: Article,,卷期:2012年109-19]
- Metacaspases are distantly related caspase-family cysteine peptidases implicated in programmed cell death in plants and lower eukaryotes. They differ significantly from caspases because they are calcium-activated, argini...
- Kaposi's sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection
[作者:Chakraborty, S; Veettil, MV; Bottero, V; Chandran, B,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:E1163-E1172 , 文章类型: Article,,卷期:2012年109-19]
- Kaposi's sarcoma-associated herpesvirus (KSHV), etiologically associated with Kaposi's sarcoma, uses integrins (alpha 3 beta 1, alpha V beta 3, and alpha V beta 5) and associated signaling to enter human dermal microvasc...
- Order parameter fluctuations at a buried quantum critical point
[作者:Feng, YJ; Wang, JY; Jaramillo, R; van Wezel, J; Haravifard, S; Srajer, G; Liu, Y; Xu, ZA; Littlewood, PB; Rosenbaum, TF,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7224-7229 , 文章类型: Article,,卷期:2012年109-19]
- Quantum criticality is a central concept in condensed matter physics, but the direct observation of quantum critical fluctuations has remained elusive. Here we present an X-ray diffraction study of the charge density wav...
- Anxiety in liver X receptor beta knockout female mice with loss of glutamic acid decarboxylase in ventromedial prefrontal cortex
[作者:Tan, XJ; Dai, YB; Wu, WF; Warner, M; Gustafsson, JA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:7493-7498 , 文章类型: Article,,卷期:2012年109-19]
- Anxiety disorders are the most prevalent mental disorders in adolescents in the United States. Female adolescents are more likely than males to be affected with anxiety disorders, but less likely to have behavioral and s...
|