- Impact of declining Arctic sea ice on winter snowfall
[作者:Liu, JP; Curry, JA; Wang, HJ; Song, MR; Horton, RM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4074-4079 , 文章类型: Article,,卷期:2012年109-11]
- While the Arctic region has been warming strongly in recent decades, anomalously large snowfall in recent winters has affected large parts of North America, Europe, and east Asia. Here we demonstrate that the decrease in...
- Fracture of crystalline silicon nanopillars during electrochemical lithium insertion
[作者:Lee, SW; McDowell, MT; Berla, LA; Nix, WD; Cui, Y,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4080-4085 , 文章类型: Article,,卷期:2012年109-11]
- From surface hardening of steels to doping of semiconductors, atom insertion in solids plays an important role in modifying chemical, physical, and electronic properties of materials for a variety of applications. High d...
- Higher social class predicts increased unethical behavior
[作者:Piff, PK; Stancato, DM; Cote, S; Mendoza-Denton, R; Keltner, D,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4086-4091 , 文章类型: Article,,卷期:2012年109-11]
- Seven studies using experimental and naturalistic methods reveal that upper-class individuals behave more unethically than lower-class individuals. In studies 1 and 2, upper-class individuals were more likely to break th...
- Gold nanoparticles as a platform for creating a multivalent poly-SUMO chain inhibitor that also augments ionizing radiation
[作者:Li, YJ; Perkins, AL; Su, Y; Ma, YL; Colson, L; Horne, DA; Chen, Y,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4092-4097 , 文章类型: Article,,卷期:2012年109-11]
- Protein-protein interactions mediated by ubiquitin-like (Ubl) modifications occur as mono-Ubl or poly-Ubl chains. Proteins that regulate poly-SUMO (small ubiquitin-like modifier) chain conjugates play important roles in ...
- Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1(A903V) and CESA3(T942I) of cellulose synthase
[作者:Harris, DM; Corbin, K; Wang, T; Gutierrez, R; Bertolo, AL; Petti, C; Smilgies, DM; Estevez, JM; Bonetta, D; Urbanowicz, BR; Ehrhardt, DW; Somerville, CR; Rose, JKC; Hong, M; DeBolt, S,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4098-4103 , 文章类型: Article,,卷期:2012年109-11]
- The mechanisms underlying the biosynthesis of cellulose in plants are complex and still poorly understood. A central question concerns the mechanism of microfibril structure and how this is linked to the catalytic polyme...
- Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation
[作者:Kapur, S; Lowry, B; Yuzawa, S; Kenthirapalan, S; Chen, AY; Cane, DE; Khosla, C,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4110-4115 , 文章类型: Article,,卷期:2012年109-11]
- Multimodular polyketide synthases (PKSs) have an assembly line architecture in which a set of protein domains, known as a module, participates in one round of polyketide chain elongation and associated chemical modificat...
- Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking
[作者:Strochlic, TI; Concilio, S; Viaud, J; Eberwine, RA; Wong, LE; Minden, A; Turk, BE; Plomann, M; Peterson, JR,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4116-4121 , 文章类型: Article,,卷期:2012年109-11]
- Synaptic transmission is mediated by a complex set of molecular events that must be coordinated in time and space. While many proteins that function at the synapse have been identified, the signaling pathways regulating ...
- Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily
[作者:Lukk, T; Sakai, A; Kalyanaraman, C; Brown, SD; Imker, HJ; Song, L; Fedorov, AA; Fedorov, EV; Toro, R; Hillerich, B; Seidel, R; Patskovsky, Y; Vetting, MW; Nair, SK; Babbitt, PC; Almo, SC; Gerlt, JA; Jacobson, MP,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4122-4127 , 文章类型: Article,,卷期:2012年109-11]
- The rapid advance in genome sequencing presents substantial challenges for protein functional assignment, with half or more of new protein sequences inferred from these genomes having uncertain assignments. The assignmen...
- Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein
[作者:Nabhan, JF; Hu, RX; Oh, RS; Cohen, SN; Lu, Q,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4146-4151 , 文章类型: Article,,卷期:2012年109-11]
- Mammalian cells are capable of delivering multiple types of membrane capsules extracellularly. The limiting membrane of late endosomes can fuse with the plasma membrane, leading to the extracellular release of multivesic...
- Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export
[作者:Ichikawa, Y; Bayeva, M; Ghanefar, M; Potini, V; Sun, L; Mutharasan, RK; Wu, RX; Khechaduri, A; Naik, TJ; Ardehali, H,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4152-4157 , 文章类型: Article,,卷期:2012年109-11]
- Mitochondrial iron levels are tightly regulated, as iron is essential for the synthesis of Fe/S clusters and heme in the mitochondria, but high levels can cause oxidative stress. The ATP-binding cassette (ABC) transporte...
- Self-incompatibility response induced by calcium increase in sperm of the ascidian Ciona intestinalis
[作者:Saito, T; Shiba, K; Inaba, K; Yamada, L; Sawada, H,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:4158-4162 , 文章类型: Article,,卷期:2012年109-11]
- Many hermaphroditic organisms possess a self-incompatibility system to avoid self-fertilization. Recently, we identified the genes responsible for self-sterility in a hermaphroditic primitive chordate (ascidian), Ciona i...
|