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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共113条记录   A Practical, One-Pot Synthesis of Highly Substituted Thiophenes and Benzo[b]thiophenes from Bromoenynes and o-Alkynylbromobenzenes [作者：GUILARTE VERONICA; FERNANDEZRODRIGUEZ MANUEL A; GARCIAGARCIA PATRICIA; HERNANDO ELSA; SANZ ROBERTO,期刊：Organic Letters, 页码：5100-5103 , 文章类型： Article，,卷期：2011年13-19] An efficient synthesis of thiophenes and benzo[b]thiophenes has been developed from easily available bromoenynes and o-alkynylbromobenzene derivatives. This novel one-pot procedure involves a Pd-catalyzed C-S bond format... Novel Approach to the Lundurine Alkaloids: Synthesis of the Tetracyclic Core [作者：ORR SUVI T M; TIAN JIANHUA; NIGGEMANN MEIKE; MARTIN STEPHEN F,期刊：Organic Letters, 页码：5104-5107 , 文章类型： Article，,卷期：2011年13-19] The tetracyclic core of the lundurine family of alkaloids has been synthesized by a novel approach that features a double ring-closing olefin metathesis to form the five-and eight-membered rings. Convergent Synthesis and Discovery of a Natural Product-Inspired Paralog-Selective Hsp90 Inhibitor [作者：JESO VALER; CHERRY LISA; MACKLIN TODD K; PAN SUBHAS CHANDRA; LOGRASSO PHILIP V; MICALIZIO GLENN C,期刊：Organic Letters, 页码：5108-5111 , 文章类型： Article，,卷期：2011年13-19] A convergent synthesis of benzoquinone ansamycin analogs is described that proceeds by a sequence of metallacycle-mediated alkyne-alkyne coupling, followed by site- and stereoselective dihydroxylation and global carbamat... Convenient Synthesis of 3-Vinyl and 3-Styryl Coumarins [作者：GORDO JOANA; AVO JOAO; PAROLA A JORGE; LIMA JOAO C; PEREIRA ANTONIO; BRANCO PAULA S,期刊：Organic Letters, 页码：5112-5115 , 文章类型： Article，,卷期：2011年13-19] A variety of 2-hydroxy aldehydes on reaction with 3-butenoic acid afford in a one-pot reaction the corresponding 3-vinylcoumarins. As expected, extension of the delocalized pi-electron system accomplished by Heck couplin... Experimental and Theoretical Studies on the Radical-Cation-Mediated Imino-Diels-Alder Reaction [作者：PEREZRUIZ RAUL; DOMINGO LUIS R; CONSUELO JIMENEZ M; MIRANDA MIGUEL A,期刊：Organic Letters, 页码：5116-5119 , 文章类型： Article，,卷期：2011年13-19] The feasibility of an electron transfer imino-Diels-Alder reaction between N-benzylideneaniline and arylalkenes in the presence of a pyrylium salt as a photosensitizer has been demonstrated by a combination of product st... Base-Catalyzed Povarov Reaction: An Unusual [1,3] Sigmatropic Rearrangement to Dihydropyrimidobenzimidazoles [作者：CHEN CHIHHAU; YELLOL GORAKH S; LIN POTSUNG; SUN CHUNGMING,期刊：Organic Letters, 页码：5120-5123 , 文章类型： Article，,卷期：2011年13-19] A novel base-catalyzed Povarov reaction of arylamines, aldehydes, and electron-deficient dienophiles has been developed. An unprecedented in situ [1,3] sigmatropic rearrangement leading to 4,10-dihydropyrimido[1,2-a]benz... Heterogeneous Catalytic Hydrogenation of Unprotected Indoles in Water: A Green Solution to a Long-Standing Challenge [作者：KULKARNI ADITYA; ZHOU WEIHONG; TOEROEK BELA,期刊：Organic Letters, 页码：5124-5127 , 文章类型： Article，,卷期：2011年13-19] An environmentally benign procedure for the hydrogenation of unprotected indoles is described. The hydrogenation reaction is catalyzed by PVC and activated by p-toluenesulfonic acid in water as a solvent. The efficacy of... Enantiodivergent Synthetic Entry to the Quinolizidine Alkaloid Lasubine II [作者：SAHA NEMAI; BISWAS TANMOY; CHATTOPADHYAY SHITAL K,期刊：Organic Letters, 页码：5128-5131 , 文章类型： Article，,卷期：2011年13-19] Intramolecular cycloaddition of the syn- and the anti-nitrone 9 and 13 leads stereoselectively to the azabicyclic compounds 10 and 14 which may provide access to both enantiomers of the quinolizidine alkaloid lasubine II... Expedient Route to the Functionalized Calyciphylline A-Type Skeleton via a Michael Addition-RCM Strategy [作者：SLADOJEVICH FILIPPO; MICHAELIDES IACOVOS N; DARSES BENJAMIN; WARD JOHN W; DIXON DARREN J,期刊：Organic Letters, 页码：5132-5135 , 文章类型： Article，,卷期：2011年13-19] An efficient, robust, and scalable strategy to access the functionalized core of calyciphylline A-type alkaloids has been developed starting from commercially available 3-methylanisole. Key features of this approach are ... Three-Component Coupling Approach to Trachyspic Acid [作者：SCHMITT DANIEL C; LAM LEIGHANN; JOHNSON JEFFREY S,期刊：Organic Letters, 页码：5136-5139 , 文章类型： Article，,卷期：2011年13-19] Three-component coupling of the lithium enolate of t-BuOAc, silyl glyoxylate, and an alpha,beta-unsaturated ketone enables the rapid construction of the trachyspic acid carbon skeleton. A 3,4-disubstituted isoxazole is u... Studies Directed toward the Elucidation of the Pharmacophore of Steroid-Based Sonic Hedgehog Signaling Inhibitors [作者：ISAACS ANDRE K; XIANG CHAOMEI; BAUBET VALERIE; DAHMANE NADIA; WINKLER JEFFREY D,期刊：Organic Letters, 页码：5140-5143 , 文章类型： Article，,卷期：2011年13-19] Previous work from our laboratory has established that the readily available steroid-based analog 2 of cyclopamine 1 is, like 1, a highly potent inhibitor of Hedgehog signaling. The first structure-activity relationship ... NRPS Substrate Promiscuity Diversifies the Xenematides [作者：CRAWFORD JASON M; PORTMANN CYRIL; KONTNIK RENEE; WALSH CHRISTOPHER T; CLARDY JON,期刊：Organic Letters, 页码：5144-5147 , 文章类型： Article，,卷期：2011年13-19] Xenematide, a cyclic depsipeptide antibiotic produced by Xenorhabdus nematophila, had a candidate nonribosomal peptide synthetase (NRPS) with atypical features. Differential metabolite analysis between a mutant and wildt... A Modular Reaction Pairing Approach to the Diversity-Oriented Synthesis of Fused- and Bridged-Polycyclic Sultams [作者：SAMARAKOON THIWANKA B; LOH JOANNA K; ROLFE ALAN; LE LISA S; YOON SUN YOUNG; LUSHINGTON GERALD H; HANSON PAUL R,期刊：Organic Letters, 页码：5148-5151 , 文章类型： Article，,卷期：2011年13-19] A reaction pairing strategy centered on utilization of a reaction triad (sulfonylation, S(N)Ar addition and Mitsunobu alkylation) generating skeletally diverse, tricyclic and bicyclic benzofused sultams is reported. Pair... Copper-Catalyzed Perkin-Acyl-Mannich Reaction of Acetic Anhydride with Pyridine: Expeditious Entry to Unconventional Piperidines [作者：CROTTI STEFANO; BERTI FRANCESCO; PINESCHI MAURO,期刊：Organic Letters, 页码：5152-5155 , 文章类型： Article，,卷期：2011年13-19] A regioselective introduction of a methoxycarbonyl methyl group at the C(2) position of unsubstituted pyridine has been accomplished with catalytic amounts of copper(II) triflate in mild reaction conditions. The N-acetyl... Synthesis of 6-Substituted-4-Hydroxy-2-pyridinones via Intramolecular Ketene Trapping of Functionalized Enamine-Dioxinones [作者：PATEL BHAVESH H; MASON ANDREW M; BARRETT ANTHONY G M,期刊：Organic Letters, 页码：5156-5159 , 文章类型： Article，,卷期：2011年13-19] The synthesis of various 6-substituted-4-hydroxy-2-pyridinones is reported. The functionalized keto-dioxinones were constructed via a diethylzinc mediated crossed Claisen condensation reaction and subsequent enamine form... Alkoxyamine-derived Formamidines: Configurational Control and Molecular Folding [作者：ZHAO WEIWEN; WANG RUIYAO; MOSEY NICHOLAS J; PETITJEAN ANNE,期刊：Organic Letters, 页码：5160-5163 , 文章类型： Article，,卷期：2011年13-19] N,N-Disubstituted formamidines, and amidines in general, have very rich configurational, conformational, and tautomeric diversities. As part of an effort to incorporate alkoxyamine-derived formamidine units into foldamer...