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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共75条记录   Target-Directed Synthesis of Antibacterial Drug Candidate GSK966587 [作者：VOIGHT ERIC A; YIN HAO; DOWNING SUSAN V; CALAD STACIE A; MATSUHASHI HAYAO; GIORDANO ILARIA; HENNESSY ALAN J; GOODMAN RICHARD M; WOOD JEFFERY L,期刊：Organic Letters, 页码：3422-3425 , 文章类型： Article，,卷期：2010年12-15] An efficient enantioselective total synthesis of the potent antibiotic GSK966587 was accomplished. Highlights of the synthesis include two innovative Heck reactions, a highly selective zincate base directed ortho-metalat... Synthesis of Fluoroazaindolines by an Uncommon Radical ipso Substitution of a Carbon-Fluorine Bond [作者：LAOT YANN; PETIT LAURENT; ZARD SAMIR Z,期刊：Organic Letters, 页码：3426-3429 , 文章类型： Article，,卷期：2010年12-15] Rare examples of a synthetically useful radical ipso substitution of a carbon fluorine bond are reported. Highly functionalized fluoroazaindoline structures have thus been prepared with use of cheap and readily available... Total Synthesis of (-)-8-Deoxyserratinine via an Efficient Helquist Annulation and Double N-Alkylation Reaction [作者：YANG YURONG; LAI ZENGWEI; SHEN LIANG; HUANG JIUZHONG; WU XINGDE; YIN JUNLIN; WEI KUN,期刊：Organic Letters, 页码：3430-3433 , 文章类型： Article，,卷期：2010年12-15] The first enantioselective total synthesis of (-)-8-deoxyserratinine has been achieved in 15 steps from enone 4 with 7% overall yield. The key features include a highly efficient Helquist annulation to furnish the cis-fu... Titanium-Mediated Spirocyclization Reactions of 4-Alkylpyridines [作者：PARAMESWARAPPA SHARAVATHI G; PIGGE F CHRISTOPHER,期刊：Organic Letters, 页码：3434-3437 , 文章类型： Article，,卷期：2010年12-15] Pyridines substituted at the 4-position with alkyl tethers containing beta-dicarbonyl moieties were converted to spirocyclic 4,4-disubstituted dihydropyridines. Optimal conditions for these transformations involved N-acy... Tuning the Optoelectronic Properties of 4,4 '-N,N '-Dicarbazole-biphenyl through Heteroatom Linkage: New Host Materials for Phosphorescent Organic Light-Emitting Diodes [作者：ZHANG SHENGLAN; CHEN RUNFENG; YIN JUN; LIU FENG; JIANG HONGJI; SHI NAIEN; AN ZHONGFU; MA CONG; LIU BIN; HUANG WEI,期刊：Organic Letters, 页码：3438-3441 , 文章类型： Article，,卷期：2010年12-15] Five carbazole end-capped heterofluorenes (CzHFs) designed by structurally mimicking 4,4'-N,N'-dicarbazole-biphenyl (CBP) via connecting the biphenyl core of CBP with the linking atom of C, P, N, O, and S, respectively, ... Synthesis of Small and Large Fused Bicyclic Compounds by Tandem Dienyne Ring-Closing Metathesis [作者：PARK HYEON; HONG YOULEE; KIM YONGJOO B; CHOI TAELIM,期刊：Organic Letters, 页码：3442-3445 , 文章类型： Article，,卷期：2010年12-15] A tandem ring-closing metathesis reaction using ruthenium catalyst was carried out to synthesize various fused bicyclic compounds containing both small and large rings. Fast ring-closure of the small ring and slow ring-c... First C-H Activation Route to Oxindoles using Copper Catalysis [作者：KLEIN JOHANNES E M N; PERRY ALEXIS; PUGH DAVID S; TAYLOR RICHARD J K,期刊：Organic Letters, 页码：3446-3449 , 文章类型： Article，,卷期：2010年12-15] The preparation of 3,3-disubstituted oxindoles by a formal C-H, Ar-H coupling of anilides is described. Highly efficient conditions have been Identified using catalytic (5 mol %) Cu(OAc)(2)center dot H2O with atmospheric... Nickel-Catalyzed [2+2+2] Cycloaddition of Two Enones and an Alkyne [作者：OGOSHI SENSUKE; NISHIMURA AKIRA; OHASHI MASATO,期刊：Organic Letters, 页码：3450-3452 , 文章类型： Article，,卷期：2010年12-15] A fully intermolecular [2 + 2 + 2] cycloaddition of two enones and an alkyne has been achieved. This reaction proceeds stereoselectively to give one diastereomer as a sole product. Total Synthesis of Syringolin A [作者：DAI CHUNHUI; STEPHENSON COREY R J,期刊：Organic Letters, 页码：3453-3455 , 文章类型： Article，,卷期：2010年12-15] A convergent, efficient synthesis of syringolin A has been accomplished in 13 steps from commercially available materials, Garner's aldehyde and L-valine. The unnatural 3,4-dehydrolysine fragment was prepared using succe... Facile Preparation of Oxazole-4-carboxylates and 4-Ketones from Aldehydes using 3-Oxazoline-4-carboxylates as Intermediates [作者：MURAI KENICHI; TAKAHARA YUSUKE; MATSUSHITA TOMOYO; KOMATSU HIDEYUKI; FUJIOKA HIROMICHI,期刊：Organic Letters, 页码：3456-3459 , 文章类型： Article，,卷期：2010年12-15] A novel 2-step synthesis of oxazole-4-carboxylates from aldehydes was developed, which Is characterized by the utilization of 3-oxazoline-4-carboxylates as synthetic Intermediates. The facile preparation of 4-keto-oxazol... One-Pot Synthesis of Well-Defined Oligo- Butadiynylene-Naphthalene Diimides [作者：YUE WAN; ZHEN YONGGANG; LI YAN; JIANG WEI; LV AIFENG; WANG ZHAOHUI,期刊：Organic Letters, 页码：3460-3463 , 文章类型： Article，,卷期：2010年12-15] A homogeneous series of well-defined oligo-butadiynylene-NDIs containing up to five naphthalene diimides (NDIs) moieties have been efficiently synthesized in one pot by oxidative homocoupling of 1,6-di((trimethylsilyl)et... Decarboxylative Acylation of Arenes with alpha-Oxocarboxylic Acids via Palladium-Catalyzed C-H Activation [作者：LI MINGZONG; GE HAIBO,期刊：Organic Letters, 页码：3464-3467 , 文章类型： Article，,卷期：2010年12-15] An efficient palladium-catalyzed decarboxylative acylation of unactivated arenes with alpha-oxocarboxylic acids is reported. This method provides a novel access to aryl ketones. Gold Catalyzed Diastereoselective Cascade Allylation/Enyne Cycloisomerization to Construct Densely Functionalized Oxygen Hetereocycles [作者：CHEN ZILI; ZHANG YUXIN; WANG YAHUI; ZHU LILI; LIU HENG; LI XIAOXIAO; GUO LIN,期刊：Organic Letters, 页码：3468-3471 , 文章类型： Article，,卷期：2010年12-15] A new tandem allylation/enyne cycloisomerization reaction was developed to construct densely functionalized oxygen hetereocycles with high diastereoselectivities from the intermolecular reaction of allylic acetates with ... A Cope Rearrangement-Based Route to Hexahydroazulenes [作者：SEIZERT CURTIS A; BUMBU VALENTINA D; BIRMAN VLADIMIR B,期刊：Organic Letters, 页码：3472-3475 , 文章类型： Article，,卷期：2010年12-15] 2-exo-Vinyl-7-alkylidenenorbornanes, readily prepared from fulvene Die Is Alder adducts, undergo smooth Cope rearrangement at elevated temperatures to produce hexahydroazulene derivatives. The Nucleophilic Reactivity of Fluoromethoxycarbene [作者：MOSS ROBERT A; ZHANG MIN; KROGHJESPERSEN KARSTEN,期刊：Organic Letters, 页码：3476-3479 , 文章类型： Article，,卷期：2010年12-15] Activation parameters are reported for the additions of fluoromethoxycarbene (FCOMe) to alpha-chloroacrylonitrile, methyl acrylate, and acrylonitrile. The reactivity of FCOMe Is compared to that of dichlorocarbene and ch... Enantioselective Wacker-Type Cyclization of 2-AlkenyL-1,3-diketones Promoted by Pd-SPRIX Catalyst [作者：TAKENAKA KAZUHIRO; MOHANTA SUMAN C; PATIL MAHESH L; RAO C V LAXMAN; TAKIZAWA SHINOBU; SUZUKI TAKEYUKI; SASAI HIROAKI,期刊：Organic Letters, 页码：3480-3483 , 文章类型： Article，,卷期：2010年12-15] An enantioselective intramolecular Wacker-type cyclization of 2-alkenyl-1,3-diketones catalyzed by a Pd(II)-SPRIX complex was developed. The reaction proceeded in a 6-endo-trig mode to give the desired chromene derivativ...