- Protein Plasticity: A Single Amino Acid Substitution in the Saccharomyces cerevisiae Oxidosqualene-Lanosterol Cyclase Generates Protosta-13(17),24-dien-3b-ol, a Rearrangement Product.
[作者:Wu, Tung-Kung;Wen, Hao-Yu;Chang, Cheng-Hsiang;Liu, Yuan-Ting;,期刊:Organic Letters, 页码:2529-2532 , 文章类型: 研究论文,,卷期:2008年10-12]
- oxidosqualene-lanosterol cyclase (ERG7) from Saccharomyces cerevisiae, the Phe699 was exchanged against hydrophilic polar uncharged residues Ser, Thr, Cys, Gln, and Tyr to characterize its product profile and functional ...
- Formation of enantiopure 5-substituted oxazolidinones through enzyme-catalyzed kinetic resolution of epoxides.
[作者:Elenkov, Maja Majeric;Tang, Lixia;Meetsma, Auke;Hauer, Bernhard;Janssen, Dick B.;,期刊:Organic Letters, 页码:2417-2420 , 文章类型: 研究论文,,卷期:2008年10-12]
- Halohydrin dehalogenase from Agrobacterium radiobacter catalyzed the enantioselective ring opening of terminal epoxides with cyanate as a nucleophile, yielding 5-substituted oxazolidinones in high yields and with high en...
- A mild, one-pot synthesis of 4-quinolones via sequential Pd-catalyzed amidation and base-promoted cyclization.
[作者:Huang, Jinkun;Chen, Ying;King, Anthony O.;Dilmeghani, Mina;Larsen, Robert D.;Faul, Margaret M.;,期刊:Organic Letters, 页码:2609-2612 , 文章类型: 研究论文,,卷期:2008年10-12]
- A mild, one-pot synthesis of 4-quinolones is described. Under the optimal conditions, a variety of 2-substituted 4-quinolones were synthesized via sequential palladium-catalyzed amidation of 2'-bromoacetophenones follow...
- Palladium-catalyzed b-allylation of 2,3-disubstituted indoles.
[作者:Kagawa, Natsuko;Malerich, Jeremiah P.;Rawal, Viresh H.;,期刊:Organic Letters, 页码:2381-2384 , 文章类型: 研究论文,,卷期:2008年10-12]
- A direct C3-functionalization of 2,3-disubstituted indoles was developed. Under palladium-phosphine catalyst, the b-allylation of 2,3-disubstituted indole derivs. with allyl carbonates was carried out smoothly with good...
- Tube and Cage C60H60: A Comparison with C60F60.
[作者:Jia, Jianfeng;Wu, Hai-Shun;Xu, Xiao-Hong;Zhang, Xian-Ming;Jiao, Haijun;,期刊:Organic Letters, 页码:2573-2576 , 文章类型: 研究论文,,卷期:2008年10-12]
- cage isomer (1) with isolated five-membered rings. Introduction of endo C-H bonds into structure 5 results in further stabilization, but the most stable tube structure with four endo C-H bonds (7) is higher in by 74.2 k...
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