- Domino Transformation of D-Glucal to Racemic a-Substituted a-Hydroxymethyl Furfuryl Derivatives.
[作者:Mukherjee, Debaraj;Yousuf, Syed Khalid;Taneja, Subhash Chandra;,期刊:Organic Letters, 页码:4831-4834 , 文章类型: 研究论文,,卷期:2008年10-21]
- Lewis acid mediated one-pot transformation of D-glucal (I) in the presence of nucleophiles leads to the formation of racemic a-substituted a-hydroxymethyl furfuryl derivs., e.g., II, versatile synthons for biol. active m...
- A Concise and Modular Synthesis of Pyranicin.
[作者:Griggs, Nolan D.;Phillips, Andrew J.;,期刊:Organic Letters, 页码:4955-4957 , 文章类型: 研究论文,,卷期:2008年10-21]
- A modular, 13-step synthesis of the tetrahydropyran-contg. annonaceous acetogenin pyranicin (I) is reported. Key features are the use of an Achmatowicz oxidn.-Kishi redn. sequence for the assembly of a pyranone from a f...
- Synthesis of amphidinolide E C10-C26 fragment.
[作者:Esteban, Jorge;Costa, Anna M.;Vilarrasa, Jaume;,期刊:Organic Letters, 页码:4843-4846 , 文章类型: 研究论文,,卷期:2008年10-21]
- The key C(10)-C(26) fragment (I) in a total synthesis of segment via Julia-Kocienski reaction with 4-bromo-2-methyl-4-pentenal, followed by a Sharpless asym. dihydroxylation to obtain the desired diol. The C(22)-C(26) f...
- Stereocontrolled Access to Isoprostanes via a Bicyclo[3.3.0]octene Framework.
[作者:Oger, Camille;Brinkmann, Yasmin;Bouazzaoui, Samira;Durand, Thierry;Galano, Jean-Marie;,期刊:Organic Letters, 页码:5087-5090 , 文章类型: 研究论文,,卷期:2008年10-21]
- We report a simple and highly stereocontrolled strategy toward the total synthesis of isoprostanes I and II based on a bicyclic a,b-epoxy ketone intermediate III. Bicyclo[3.3.0]octene scaffold permitted stereodirection ...
- Overcoming the Limitations of the Morita-Baylis-Hillman Reaction: A Rapid and General Synthesis of a-Alkenyl-b'-hydroxy Thioesters.
[作者:Tarsis, Emily;Gromova, Anna;Lim, Daniel;Zhou, Guoqiang;Coltart, Don M.;,期刊:Organic Letters, 页码:4819-4822 , 文章类型: 研究论文,,卷期:2008年10-21]
- Acryloyl chlorides, aldehydes, and PhSLi undergo a direct aldol cascade sequence in the presence of MgBr2譕Et2 via in situ derived thioester enolates, which is followed by oxidative elimination to give a-alkenyl-b'-hydrox...
- Enyne Cross-Metathesis with Strained, Geminally-Substituted Alkenes: Direct Access to Highly Substituted 1,3-Dienes.
[作者:Clark, Daniel A.;Basile, Brenda S.;Karnofel, William S.;Diver, Steven T.;,期刊:Organic Letters, 页码:4927-4929 , 文章类型: 研究论文,,卷期:2008年10-21]
- metathesis with 1-alkynes, giving 1,1,3-trisubstituted 1,3-dienes in good isolated yields. An extensive survey of Grubbs' second-generation catalysts led to an optimized reaction conducted at 0 癈.
- L-Selectride-Mediated Highly Diastereoselective Asymmetric Reductive Aldol Reaction: Access to an Important Subunit for Bioactive Molecules.
[作者:Ghosh, Arun K.;Kass, Jorden;Anderson, David D.;Xu, Xiaoming;Marian, Christine;,期刊:Organic Letters, 页码:4811-4814 , 文章类型: 研究论文,,卷期:2008年10-21]
- L-Selectride redn. of a chiral or achiral enone followed by reaction of the resulting enolate with optically active a-alkoxy aldehydes proceeded with excellent diastereoselectivity. The resulting a,a-dimethyl-b-hydroxy ...
- Importance of Saccharomyces cerevisiae Oxidosqualene-Lanosterol Cyclase Tyrosine 707 Residue for Chair-Boat Bicyclic Ring Formation and Deprotonation Reactions.
[作者:Wu, Tung-Kung;Wang, Tsai-Ting;Chang, Cheng-Hsiang;Liu, Yuan-Ting;Shie, Wen-Shiang;,期刊:Organic Letters, 页码:4959-4962 , 文章类型: 研究论文,,卷期:2008年10-21]
- A contact mapping strategy was applied to identify putative amino acid residues that influence the oxidosqualene-lanosterol B-ring cyclization reaction. A bicyclic intermediate with two altered deprotonation products, i...
- B,O-Chelated azadipyrromethenes as near-IR probes.
[作者:Loudet, Aurore;Bandichhor, Rakeshwar;Burgess, Kevin;Palma, Aniello;McDonnell, Shane O.;Hall, Michael J.;O'Shea, Donal F.;,期刊:Organic Letters, 页码:4771-4774 , 文章类型: 研究论文,,卷期:2008年10-21]
- Fluorescent Brighteners, and Photographic Sensitizers) Section Complementary synthetic routes to a new class of near-IR fluorophores are described. These allow facile access (four synthetic steps) to the core fluorophor...
- Syntheses of a- and b-C-glucopyranosyl serines from a common intermediate.
[作者:Nolen, Ernest G.;Donahue, Laurence A.;Greaves, Rebecca;Daly, Trevor A.;Calabrese, David R.;,期刊:Organic Letters, 页码:4911-4914 , 文章类型: 研究论文,,卷期:2008年10-21]
- A versatile synthesis leading to either C-linked a- or b-glucopyranosyl serines is presented from a common, advanced synthetic intermediate, oxepenone (I) (Boc = tertbutoxycarbonyl). Oxepenone I is available through a R...
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