- HIV Infection Abrogates the Functional Advantage of Natural Killer Cells Educated through KIR3DL1/HLA-Bw4 Interactions To Mediate Anti-HIV Antibody-Dependent Cellular Cytotoxicity
[作者:Parsons, MS; Wren, L; Isitman, G; Navis, M; Stratov, I; Bernard, NF; Kent, SJ,期刊:Journal of virology, 页码:4488-4495 , 文章类型: Article,,卷期:2012年86-8]
- Combinations of KIR3DL1 and HLA-Bw4 alleles protect against HIV infection and/or disease progression. These combinations enhance NK cell responsiveness through the ontological process of education. However, educated KIR3...
- The Human Immunodeficiency Virus Type 1 Nef and Vpu Proteins Downregulate the Natural Killer Cell-Activating Ligand PVR
[作者:Matusali, G; Potesta, M; Santoni, A; Cerboni, C; Doria, M,期刊:Journal of virology, 页码:4496-4504 , 文章类型: Article,,卷期:2012年86-8]
- The human immunodeficiency virus type 1 (HIV-1) evades the immune responses of natural killer (NK) cells through mechanisms that have been partially deciphered. Here we show that in HIV-1-infected T lymphocytes, the earl...
- Passively Transmitted gp41 Antibodies in Babies Born from HIV-1 Subtype C-Seropositive Women: Correlation between Fine Specificity and Protection
[作者:Diomede, L; Nyoka, S; Pastori, C; Scotti, L; Zambon, A; Sherman, G; Gray, CM; Sarzotti-Kelsoe, M; Lopalco, L,期刊:Journal of virology, 页码:4129-4138 , 文章类型: Article,,卷期:2012年86-8]
- HIV-exposed, uninfected (EUN) babies born to HIV-infected mothers are examples of natural resistance to HIV infection. In this study, we evaluated the titer and neutralizing potential of gp41-specific maternal antibodies...
- Enhanced Susceptibility of Ago1/3 Double-Null Mice to Influenza A Virus Infection
[作者:Van Stry, M; Oguin, TH; Cheloufi, S; Vogel, P; Watanabe, M; Pillai, MR; Dash, P; Thomas, PG; Hannon, GJ; Bix, M,期刊:Journal of virology, 页码:4151-4157 , 文章类型: Article,,卷期:2012年86-8]
- RNA interference (RNAi) is a critical component of many cellular antiviral responses in plants, invertebrates, and mammals. However, its in vivo role in host protection from the negative-sense RNA virus influenza virus t...
- Interleukin-27 Inhibits Vaccine-Enhanced Pulmonary Disease following Respiratory Syncytial Virus Infection by Regulating Cellular Memory Responses
[作者:Zeng, RH; Zhang, HX; Hai, Y; Cui, YX; Wei, L; Li, N; Liu, JX; Li, CX; Liu, Y,期刊:Journal of virology, 页码:4505-4517 , 文章类型: Article,,卷期:2012年86-8]
- Respiratory syncytial virus (RSV) is the most important cause of lower respiratory tract disease in young children. In the 1960s, infants vaccinated with formalin-inactivated RSV developed a more severe disease character...
- Mucosal Simian Immunodeficiency Virus Transmission in African Green Monkeys: Susceptibility to Infection Is Proportional to Target Cell Availability at Mucosal Sites
[作者:Pandrea, I; Parrish, NF; Raehtz, K; Gaufin, T; Barbian, HJ; Ma, DZ; Kristoff, J; Gautam, R; Zhong, F; Haret-Richter, GS; Trichel, A; Shaw, GM; Hahn, BH; Apetrei, C,期刊:Journal of virology, 页码:4158-4168 , 文章类型: Article,,卷期:2012年86-8]
- African green monkeys (AGMs) are naturally infected with a simian immunodeficiency virus (SIVagm) that is nonpathogenic in its host. Although SIVagm is common and widespread, little is known about the mechanisms that gov...
- Budding of Retroviruses Utilizing Divergent L Domains Requires Nucleocapsid
[作者:Bello, NF; Dussupt, V; Sette, P; Rudd, V; Nagashima, K; Bibollet-Ruche, F; Chen, CP; Montelaro, RC; Hahn, BH; Bouamr, F,期刊:Journal of virology, 页码:4182-4193 , 文章类型: Article,,卷期:2012年86-8]
- We recently reported that human immunodeficiency virus type 1 (HIV-1) carrying PTAP and LYPXnL L domains ceased budding when the nucleocapsid (NC) domain was mutated, suggesting a role for NC in HIV-1 release. Here we in...
- C7L Family of Poxvirus Host Range Genes Inhibits Antiviral Activities Induced by Type I Interferons and Interferon Regulatory Factor 1
[作者:Meng, XZ; Schoggins, J; Rose, L; Cao, JX; Ploss, A; Rice, CM; Xiang, Y,期刊:Journal of virology, 页码:4538-4547 , 文章类型: Article,,卷期:2012年86-8]
- Vaccinia virus (VACV) K1L and C7L function equivalently in many mammalian cells to support VACV replication and antagonize antiviral activities induced by type I interferons (IFNs). While K1L is limited to orthopoxviruse...
- Kinase Control Prevents HIV-1 Reactivation in Spite of High Levels of Induced NF-kappa B Activity
[作者:Wolschendorf, F; Bosque, A; Shishido, T; Duverger, A; Jones, J; Planelles, V; Kutsch, O,期刊:Journal of virology, 页码:4548-4558 , 文章类型: Article,,卷期:2012年86-8]
- Despite its clinical importance, the molecular biology of HIV-1 latency control is at best partially understood, and the literature remains conflicting. The most recent description that latent HIV-1 is integrated into ac...
- Susceptibility to Acute Mouse Adenovirus Type 1 Respiratory Infection and Establishment of Protective Immunity in Neonatal Mice
[作者:Procario, MC; Levine, RE; McCarthy, MK; Kim, E; Zhu, LQ; Chang, CH; Hershenson, MB; Weinberg, JB,期刊:Journal of virology, 页码:4194-4203 , 文章类型: Article,,卷期:2012年86-8]
- There is an incomplete understanding of the differences between neonatal immune responses that contribute to the increased susceptibility of neonates to some viral infections. We tested the hypothesis that neonates are m...
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