- Identification of Novel Positive-Strand RNA Viruses by Metagenomic Analysis of Archaea-Dominated Yellowstone Hot Springs
[作者:Bolduc, B; Shaughnessy, DP; Wolf, YI; Koonin, EV; Roberto, FF; Young, M,期刊:Journal of virology, 页码:5562-5573 , 文章类型: Article,,卷期:2012年86-10]
- There are no known RNA viruses that infect Archaea. Filling this gap in our knowledge of viruses will enhance our understanding of the relationships between RNA viruses from the three domains of cellular life and, in par...
- Suppression of Injuries Caused by a Lytic RNA Virus (Mengovirus) and Their Uncoupling from Viral Reproduction by Mutual Cell/Virus Disarmament
[作者:Mikitas, OV; Ivin, YY; Golyshev, SA; Povarova, NV; Galkina, SI; Pletjushkina, OY; Nadezhdina, ES; Gmyl, AP; Agol, VI,期刊:Journal of virology, 页码:5574-5583 , 文章类型: Article,,卷期:2012年86-10]
- Viruses often elicit cell injury (cytopathic effect [CPE]), a major cause of viral diseases. CPE is usually considered to be a prerequisite for and/or consequence of efficient viral growth. Recently, we proposed that vir...
- Murine Noroviruses Bind Glycolipid and Glycoprotein Attachment Receptors in a Strain-Dependent Manner
[作者:Taube, S; Perry, JW; McGreevy, E; Yetming, K; Perkins, C; Henderson, K; Wobus, CE,期刊:Journal of virology, 页码:5584-5593 , 文章类型: Article,,卷期:2012年86-10]
- Human norovirus infections are the most common cause of acute nonbacterial gastroenteritis in humans worldwide, and glycan binding plays an important role in the susceptibility to these infections. However, due to the la...
- Vaccinia Virus A6 Is Essential for Virion Membrane Biogenesis and Localization of Virion Membrane Proteins to Sites of Virion Assembly
[作者:Meng, XZ; Embry, A; Rose, L; Yan, B; Xu, CG; Xiang, Y,期刊:Journal of virology, 页码:5603-5613 , 文章类型: Article,,卷期:2012年86-10]
- Poxvirus acquires its primary envelope through a process that is distinct from those of other enveloped viruses. The molecular mechanism of this process is poorly understood, but several poxvirus proteins essential for t...
- Mouse Prion Protein (PrP) Segment 100 to 104 Regulates Conversion of PrPC to PrPSc in Prion-Infected Neuroblastoma Cells
[作者:Hara, H; Okemoto-Nakamura, Y; Shinkai-Ouchi, F; Hanada, K; Yamakawa, Y; Hagiwara, K,期刊:Journal of virology, 页码:5626-5636 , 文章类型: Article,,卷期:2012年86-10]
- Prion diseases are characterized by the replicative propagation of disease-associated forms of prion protein (PrPSc; PrP refers to prion protein). The propagation is believed to proceed via two steps; the initial binding...
- The PSAP Motif within the ORF3 Protein of an Avian Strain of the Hepatitis E Virus Is Not Critical for Viral Infectivity In Vivo but Plays a Role in Virus Release
[作者:Kenney, SP; Pudupakam, RS; Huang, YW; Pierson, FW; LeRoith, T; Meng, XJ,期刊:Journal of virology, 页码:5637-5646 , 文章类型: Article,,卷期:2012年86-10]
- The ORF3 protein of hepatitis E virus (HEV) is a multifunctional protein important for virus replication. The ORF3 proteins from human, swine, and avian strains of HEY contain a conserved PXXP amino acid motif, resemblin...
- RNA Interference-Mediated Targeting of Human Cytomegalovirus Immediate-Early or Early Gene Products Inhibits Viral Replication with Differential Effects on Cellular Functions
[作者:E, XF; Stadler, BM; Debatis, M; Wang, SX; Lu, S; Kowalik, TF,期刊:Journal of virology, 页码:5660-5673 , 文章类型: Article,,卷期:2012年86-10]
- Viral drug toxicity, resistance, and an increasing immunosuppressed population warrant continued research into new avenues for limiting diseases associated with human cytomegalovirus (HCMV). In this study, a small interf...
- Human SCARB2-Dependent Infection by Coxsackievirus A7, A14, and A16 and Enterovirus 71
[作者:Yamayoshi, S; Iizuka, S; Yamashita, T; Minagawa, H; Mizuta, K; Okamoto, M; Nishimura, H; Sanjoh, K; Katsushima, N; Itagaki, T; Nagai, Y; Fujii, K; Koike, S,期刊:Journal of virology, 页码:5686-5696 , 文章类型: Article,,卷期:2012年86-10]
- Human enterovirus species A (HEY-A) consists of at least 16 members of different serotypes that are known to be the causative agents of hand, foot, and mouth disease (HFMD), herpangina, and other diseases, such as respir...
- Adaptation of a Genotype 3 Hepatitis E Virus to Efficient Growth in Cell Culture Depends on an Inserted Human Gene Segment Acquired by Recombination
[作者:Shukla, P; Nguyen, HT; Faulk, K; Mather, K; Torian, U; Engle, RE; Emerson, SU,期刊:Journal of virology, 页码:5697-5707 , 文章类型: Article,,卷期:2012年86-10]
- An infectious cDNA clone of a genotype 3 strain of hepatitis E virus adapted to growth in HepG2/C3A human hepatoma cells was constructed. This virus was unusual in that the hypervariable region of the adapted virus conta...
- West Nile Virus Noncoding Subgenomic RNA Contributes to Viral Evasion of the Type I Interferon-Mediated Antiviral Response
[作者:Schuessler, A; Funk, A; Lazear, HM; Cooper, DA; Torres, S; Daffis, S; Jha, BK; Kumagai, Y; Takeuchi, O; Hertzog, P; Silverman, R; Akira, S; Barton, DJ; Diamond, MS; Khromykh, AA,期刊:Journal of virology, 页码:5708-5718 , 文章类型: Article,,卷期:2012年86-10]
- We previously showed that a noncoding subgenomic flavivirus RNA (sfRNA) is required for viral pathogenicity, as a mutant West Nile virus (WNV) deficient in sfRNA production replicated poorly in wild-type mice. To investi...
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