- Potent Intratype Neutralizing Activity Distinguishes Human Immunodeficiency Virus Type 2 (HIV-2) from HIV-1
[作者:Sahin, GO; Holmgren, B; da Silva, Z; Nielsen, J; Nowroozalizadeh, S; Esbjornsson, J; Mansson, F; Andersson, S; Norrgren, H; Aaby, P; Jansson, M; Fenyo, EM,期刊:Journal of virology, 页码:961-971 , 文章类型: Article,,卷期:2012年86-2]
- HIV-2 has a lower pathogenicity and transmission rate than HIV-1. Neutralizing antibodies could be contributing to these observations. Here we explored side by side the potency and breadth of intratype and intertype neut...
- Migration of Norway Rats Resulted in the Worldwide Distribution of Seoul Hantavirus Today
[作者:Lin, XD; Guo, WP; Wang, W; Zou, Y; Hao, ZY; Zhou, DJ; Dong, X; Qu, YG; Li, MH; Tian, HF; Wen, JF; Plyusnin, A; Xu, JG; Zhang, YZ,期刊:Journal of virology, 页码:972-981 , 文章类型: Article,,卷期:2012年86-2]
- Despite the worldwide distribution, most of the known Seoul viruses (SEOV) are closely related to each other. In this study, the Mand the S segment sequences of SEOV were recovered from 130 lung tissue samples (mostly of...
- Mucosal and Peripheral Lin(-) HLA-DR(+) CD11c/123(-) CD13(+) CD14(-) Mononuclear Cells Are Preferentially Infected during Acute Simian Immunodeficiency Virus Infection
[作者:Moore, AC; Bixler, SL; Lewis, MG; Verthelyi, D; Mattapallil, JJ,期刊:Journal of virology, 页码:1069-1078 , 文章类型: Article,,卷期:2012年86-2]
- Massive infection of memory CD4T cells is a hallmark of early simian immunodeficiency virus (SIV) infection, with viral infection peaking at day 10 postinfection (p.i.), when a majority of memory CD4T cells in mucosal an...
- Hepatitis C Virus Fails To Activate NF-kappa B Signaling in Plasmacytoid Dendritic Cells
[作者:Dental, C; Florentin, J; Aouar, B; Gondois-Rey, F; Durantel, D; Baumert, TF; Nunes, JA; Olive, D; Hirsch, I; Stranska, R,期刊:Journal of virology, 页码:1090-1096 , 文章类型: Article,,卷期:2012年86-2]
- Plasmacytoid dendritic cells (pDCs) respond to viral infection by production of alpha interferon (IFN-alpha), proinflammatory cytokines, and cell differentiation. The elimination of hepatitis C virus (HCV) in more than 5...
- Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induction by Hypoxia and Hypoxia-Inducible Factors
[作者:Veeranna, RP; Haque, M; Davis, DA; Yang, M; Yarchoan, R,期刊:Journal of virology, 页码:1097-1108 , 文章类型: Article,,卷期:2012年86-2]
- Hypoxia and hypoxia-inducible factors (HIFs) play an important role in the Kaposi's sarcoma-associated herpesvirus (KSHV) life cycle. In particular, hypoxia can activate lytic replication of KSHV and specific lytic genes...
- The Virion-Associated Open Reading Frame 49 of Murine Gammaherpesvirus 68 Promotes Viral Replication both In Vitro and In Vivo as a Derepressor of RTA
[作者:Noh, CW; Cho, HJ; Kang, HR; Jin, HY; Lee, S; Deng, HY; Wu, TT; Arumugaswami, V; Sun, R; Song, MJ,期刊:Journal of virology, 页码:1109-1118 , 文章类型: Article,,卷期:2012年86-2]
- Replication and transcription activator (RTA), an immediate-early gene, is a key molecular switch to evoke lytic replication of gammaherpesviruses. Open reading frame 49 (ORF49) is conserved among gammaherpesviruses and ...
- HIV-1 Clinical Isolates Resistant to CCR5 Antagonists Exhibit Delayed Entry Kinetics That Are Corrected in the Presence of Drug
[作者:Putcharoen, O; Lee, SH; Henrich, TJ; Hu, ZX; Vanichanan, J; Coakley, E; Greaves, W; Gulick, RM; Kuritzkes, DR; Tsibris, AMN,期刊:Journal of virology, 页码:1119-1128 , 文章类型: Article,,卷期:2012年86-2]
- HIV CCR5 antagonists select for env gene mutations that enable virus entry via drug-bound coreceptor. To investigate the mechanisms responsible for viral adaptation to drug-bound coreceptor-mediated entry, we studied vir...
- Duck Hepatitis A Virus Possesses a Distinct Type IV Internal Ribosome Entry Site Element of Picornavirus
[作者:Pan, M; Yang, XR; Zhou, L; Ge, XN; Guo, X; Liu, JH; Zhang, DB; Yang, HC,期刊:Journal of virology, 页码:1129-1144 , 文章类型: Article,,卷期:2012年86-2]
- Sequence analysis of duck hepatitis virus type 1 (DHV-1) led to its classification as the only member of a new genus, Avihepatovirus, of the family Picornaviridae, and so was renamed duck hepatitis A virus (DHAV). The 5'...
- Marked Endotheliotropism of Highly Pathogenic Avian Influenza Virus H5N1 following Intestinal Inoculation in Cats
[作者:Reperant, LA; van de Bildt, MWG; van Amerongen, G; Leijten, LME; Watson, S; Palser, A; Kellam, P; Eissens, AC; Frijlink, HW; Osterhaus, ADME; Kuiken, T,期刊:Journal of virology, 页码:1158-1165 , 文章类型: Article,,卷期:2012年86-2]
- Highly pathogenic avian influenza virus (HPAIV) H5N1 can infect mammals via the intestine; this is unusual since influenza viruses typically infect mammals via the respiratory tract. The dissemination of HPAIV H5N1 follo...
- For Protection from HIV-1 Infection, More Might Not Be Better: a Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection
[作者:Luo, M; Daniuk, CA; Diallo, TO; Capina, RE; Kimani, J; Wachihi, C; Kimani, M; Bielawny, T; Peterson, T; Mendoza, MGR; Kiazyk, S; Ball, TB; Plummer, FA,期刊:Journal of virology, 页码:1166-1180 , 文章类型: Article,,卷期:2012年86-2]
- A subset of women in the Pumwani Sex Worker Cohort, established in 1985 in Nairobi, Kenya, remains uninfected despite repeated high-risk exposure (HIV-exposed, seronegative [HESN]) through active sex work. This HESN phen...
- Viral Adaptation to Host Immune Responses Occurs in Chronic Hepatitis B Virus (HBV) Infection, and Adaptation Is Greatest in HBV e Antigen-Negative Disease
[作者:Desmond, CP; Gaudieri, S; James, IR; Pfafferott, K; Chopra, A; Lau, GK; Audsley, J; Day, C; Chivers, S; Gordon, A; Revill, PA; Bowden, S; Ayres, A; Desmond, PV; Thompson, AJ; Roberts, SK; Locarnini, SA; Mallal, SA; Lewin, SR,期刊:Journal of virology, 页码:1181-1192 , 文章类型: Article,,卷期:2012年86-2]
- Hepatitis B virus (HBV)-specific T-cell responses are important in the natural history of HBV infection. The number of known HBV-specific T-cell epitopes is limited, and it is not clear whether viral evolution occurs in ...
- Dynamics of Simian Immunodeficiency Virus SIVmac239 Infection in Pigtail Macaques
[作者:Klatt, NR; Canary, LA; Vanderford, TH; Vinton, CL; Engram, JC; Dunham, RM; Cronise, HE; Swerczek, JM; Lafont, BAP; Picker, LJ; Silvestri, G; Brenchley, JM,期刊:Journal of virology, 页码:1203-1213 , 文章类型: Article,,卷期:2012年86-2]
- Pigtail macaques (PTM) are an excellent model for HIV research; however, the dynamics of simian immunodeficiency virus (SIV) SIVmac239 infection in PTM have not been fully evaluated. We studied nine PTM prior to infectio...
- Genetic Mapping of a Highly Variable Norovirus GII.4 Blockade Epitope: Potential Role in Escape from Human Herd Immunity
[作者:Debbink, K; Donaldson, EF; Lindesmith, LC; Baric, RS,期刊:Journal of virology, 页码:1214-1226 , 文章类型: Article,,卷期:2012年86-2]
- Noroviruses account for 96% of viral gastroenteritis cases worldwide, with GII.4 strains responsible >80% of norovirus outbreaks. Histo-blood group antigens (HBGAs) are norovirus binding ligands, and antigenic and prefer...
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