- Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation
[作者:del Puerto, A; Diaz-Hernandez, JI; Tapia, M; Gomez-Villafuertes, R; Benitez, MJ; Zhang, J; Miras-Portugal, MT; Wandosell, F; Diaz-Hernandez, M; Garrido, JJ,期刊:Journal of cell science, 页码:176-188 , 文章类型: Article,,卷期:2012年125-1]
- In adult brains, ionotropic or metabotropic purinergic receptors are widely expressed in neurons and glial cells. They play an essential role in inflammation and neurotransmission in response to purines secreted to the e...
- Soluble molecules are key in maintaining the immunomodulatory activity of murine mesenchymal stromal cells
[作者:Liu, H; Lu, K; MacAry, PA; Wong, KL; Heng, A; Cao, T; Kemeny, DM,期刊:Journal of cell science, 页码:200-208 , 文章类型: Article,,卷期:2012年125-1]
- Mesenchymal stromal cells (MSCs) possess both immuno-privileged and immuno-inhibitory properties that contribute to their therapeutic effects. Ex vivo expansion is required to obtain sufficient cells for therapy, but mig...
- Annexin A5 stimulates autophagy and inhibits endocytosis
[作者:Ghislat, G; Aguado, C; Knecht, E,期刊:Journal of cell science, 页码:92-107 , 文章类型: Article,,卷期:2012年125-1]
- Macroautophagy is a major lysosomal catabolic process activated particularly under starvation in eukaryotic cells. A new organelle, the autophagosome, engulfs cytoplasmic substrates, which are degraded after fusion with ...
- Liprin-alpha controls stress fiber formation by binding to mDia and regulating its membrane localization
[作者:Sakamoto, S; Ishizaki, T; Okawa, K; Watanabe, S; Arakawa, T; Watanabe, N; Narumiya, S,期刊:Journal of cell science, 页码:108-120 , 文章类型: Article,,卷期:2012年125-1]
- Regulation of the actin cytoskeleton is crucial for cell morphology and migration. mDia is an actin nucleator that produces unbranched actin filaments downstream of Rho. However, the mechanisms by which mDia activity is ...
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