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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共58条记录   Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules [作者：CHOOI YITHENG; TANG YI,期刊：Journal of Organic Chemistry, 页码：9933-9953 , 文章类型： Article，,卷期：2012年77-22] The iterative type I polyketide synthases (IPKSs) are central to the biosynthesis of an enormously diverse array of natural products in fungi. These natural products, known as polyketides, exhibit a wide range of biologi... Silyl-Based Alkyne-Modifying Linker for the Preparation of C-Terminal Acetylene-Derivatized Protected Peptides [作者：STRACK MARTIN; LANGKLOTZ SINA; BANDOW JULIA E; METZLERNOLTE NILS; ALBADA H BAUKE,期刊：Journal of Organic Chemistry, 页码：9954-9958 , 文章类型： Article，,卷期：2012年77-22] A novel linker for the synthesis of C-terminal acetylene-functionalized protected peptides is described. This SAM1 linker is applied in the manual Fmoc-based solid-phase peptide synthesis of Leu-enkephalin and in microwa... Radical Amination of C(sp(3))-H Bonds Using N-Hydroxyphthalimide and Dialkyl Azodicarboxylate [作者：AMAOKA YUUKI; KAMIJO SHIN; HOSHIKAWA TAMAKI; INOUE MASAYUKI,期刊：Journal of Organic Chemistry, 页码：9959-9969 , 文章类型： Article，,卷期：2012年77-22] A direct conversion of C(sp(3))-H bonds to C(sp3)-N bonds has been achieved by utilizing catalytic N-hydroxyphthalimide (NHPI) and stoichiometric dialkyl azodicarboxylate. NHPI functions as a precursor of the electron-de... Macrocyclic Molecular Rotors with Bridged Steroidal Frameworks [作者：CZAJKOWSKASZCZYKOWSKA DOROTA; RODRIGUEZMOLINA BRAULIO; MAGANAVERGARA NANCY E; SANTILLAN ROSA; MORZYCKI JACEK W; GARCIAGARIBAY MIGUEL A,期刊：Journal of Organic Chemistry, 页码：9970-9978 , 文章类型： Article，,卷期：2012年77-22] In this work, we describe the synthesis and solid-state dynamics of isomeric molecular rotors 7E and 7Z, consisting of two androstane steroidal frameworks linked by the D rings by triple bonds at their C17 positions to a... Palladium-Catalyzed Annulation of 2,2 '-Diiodobiphenyls with Alkynes: Synthesis and Applications of Phenanthrenes [作者：LIN YUDE; CHO CHUNLUNG; KO CHIHWEI; PULTE ANNA; WU YAOTING,期刊：Journal of Organic Chemistry, 页码：9979-9988 , 文章类型： Article，,卷期：2012年77-22] A range of phenanthrene derivatives were efficiently synthesized by the palladium-catalyzed annulation of 2,2'-diiodobiphenyls with alkynes. The scope, limitations and regioselectivity of the reaction were investigated. ... Selective Cross-Coupling of Organic Halides with Allylic Acetates [作者：ANKALUFFORD LUKIANA L; PRINSELL MICHAEL R; WEIX DANIEL J,期刊：Journal of Organic Chemistry, 页码：9989-10000 , 文章类型： Article，,卷期：2012年77-22] A general protocol for the coupling of haloarenes with a variety of allylic acetates is presented. Strengths of the method are a tolerance for electrophilic (ketone, aldehyde) and acidic (sulfonamide, trifluoroacetamide)... Switching the Stereochemical Outcome of 6-Endo-Trig Cyclizations; Synthesis of 2,6-Cis-6-Substituted 4-Oxopipecolic Acids [作者：DALY MARK; CANT ALASTAIR A; FOWLER LINDSAY S; SIMPSON GRAHAM L; SENN HANS MARTIN; SUTHERLAND ANDREW,期刊：Journal of Organic Chemistry, 页码：10001-10009 , 文章类型： Article，,卷期：2012年77-22] A base-mediated 6-endo-trig cyclization of readily accessible enone-derived alpha-amino acids has been developed for the direct synthesis of novel 2,6-cis-6-substituted-4-oxo-L-pipecolic acids. A range of aliphatic and a... Total Synthesis and Absolute Configuration of Curvularides A-E [作者：SUDHAKAR GANGARAJULA; SATISH KOVELA; RAGHAVAIAH JAKKA,期刊：Journal of Organic Chemistry, 页码：10010-10020 , 文章类型： Article，,卷期：2012年77-22] The first total synthesis of curvularides A-E, isolated from a culture broth of the endophytic fungus Curvularia geniculata, is described. The divergent total synthesis reported herein confirmed the absolute configuratio... On the Preparation and Determination of Configurational Stability of Chiral Thio- and Bromo[D-1]methyllithiums [作者：WIECZOREK ANNA; HAMMERSCHMIDT FRIEDRICH,期刊：Journal of Organic Chemistry, 页码：10021-10034 , 文章类型： Article，,卷期：2012年77-22] Thio- and bromo[D-1]methyllithiums (ee 99%) were generated from the respective stannanes by tin-lithium exchange at temperatures ranging from 0 to -95 degrees C. Thio[D-1]methyllithiums 6 were found to be microscopically... Synthesis and Characterization of a Series of Annelated Benzotriazole Based Polymers with Variable Bandgap [作者：TAM TECK LIP DEXTER; YE WANTING; TAN HONG HUP RONNIE; ZHOU FENG; SU HAIBIN; MHAISALKAR SUBODH G; GRIMSDALE ANDREW C,期刊：Journal of Organic Chemistry, 页码：10035-10041 , 文章类型： Article，,卷期：2012年77-22] Here we report the synthesis and characterization of a series of annelated benzotriazole based polymers with variable bandgap. Benzobistriazole monomers reported by us previously were desymmetrized using partial reductio... Role of the P-F Bond in Fluoride-Promoted Aqueous VX Hydrolysis: An Experimental and Theoretical Study [作者：MARCIANO DANIELE; COLUMBUS ISHAY; ELIAS SHLOMI; GOLDVASER MICHAEL; SHOSHANIM OFIR; ASHKENAZI NISSAN; ZAFRANI YOSSI,期刊：Journal of Organic Chemistry, 页码：10042-10049 , 文章类型： Article，,卷期：2012年77-22] Following our ongoing studies on the reactivity of the fluoride ion toward organophosphorus compounds, we established that the extremely toxic and environmentally persistent chemical warfare agent VX (O-ethyl S-2-(diisop... Synthesis of Spiropiperidine Lactam Acetyl-CoA Carboxylase Inhibitors [作者：HUARD KIM; BAGLEY SCOTT W; MENHAJIKLOTZ ELNAZ; PREVILLE CATHY; SOUTHERS JAMES A; SMITH AARON C; EDMONDS DAVID J; LUCAS JOHN C; DUNN MATTHEW F; ALLANSON NIGEL M; BLANEY EMMA L; GARCIAIRIZARRY CARMEN N; KOHRT JEFFREY T; GRIFFITH DAVID A; DOW ROBERT L,期刊：Journal of Organic Chemistry, 页码：10050-10057 , 文章类型： Article，,卷期：2012年77-22] The synthesis of 4',6'-dihydrospiro[piperidine-4,5'-pyrazolo[3,4-c]pyridin]-7'(2'H)-one-based acetyl-CoA carboxylase inhibitors is reported. The hitherto unknown N-2 tert-butyl pyrazolospirolactam core was synthesized fr... Synthesis of Cyclic Peptides Containing a Thioester Handle for Native Chemical Ligation [作者：VAN DE LANGEMHEEN HELMUS; BROUWER ARWIN J; KEMMINK JOHAN; KRUIJTZER JOHN A W; LISKAMP ROB M J,期刊：Journal of Organic Chemistry, 页码：10058-10064 , 文章类型： Article，,卷期：2012年77-22] The synthesis of cyclic peptides containing a thioester handle using a sulfo-click linker is reported. These cyclic peptides can be coupled to N-terminal cysteine-containing constructs via native chemical ligation. A suc... Theoretical Study on Cyclopropanation of endo-Dicyclopentadiene with Zinc Carbenoids: Effects of Solvent and (ICH2)(2)Zn [作者：FENG REN; ZOU JIJUN; ZHANG XIANGWEN; WANG LI; ZHAO HAITAO,期刊：Journal of Organic Chemistry, 页码：10065-10072 , 文章类型： Article，,卷期：2012年77-22] A computational study using a hybrid DFT method (M06) on the cyclopropanation of endo-dicyclopentadiene with Simmons-Smith zinc carbenoids is reported. Each channel proceeds via the methylene-transfer mechanism with a re... Synthesis, Structure and Metal Binding Property of Internally 1,3-Arylene-Bridged Azacalix[6]aromatics [作者：FANG YIXIN; ZHAO LIANG; WANG DEXIAN; WANG MEIXIANG,期刊：Journal of Organic Chemistry, 页码：10073-10082 , 文章类型： Article，,卷期：2012年77-22] Three internally 1,3-arylene-bridged azacalix[6]aromatics 1-3 were synthesized by the Pd-catalyzed macrocyclic fragment coupling reaction between a stellated dibrominated pentamer and N-2,N-6-dimethylpyridine-2,6-diamine... Ion Pair Recognition Receptor Based on an Unsymmetrically 1,1 '-Disubstituted Ferrocene-Triazole Derivative [作者：OTON FRANCISCO; DEL CARMEN GONZALEZ MARIA; ESPINOSA ARTURO; RAMIREZ DE ARELLANO CARMEN; TARRAGA ALBERTO; MOLINA PEDRO,期刊：Journal of Organic Chemistry, 页码：10083-10092 , 文章类型： Article，,卷期：2012年77-22] The ferrocene-triazole derivative 4, available from 1,1'-bis(diazido)ferrocene by sequential functionalization through click-type chemistry and the Staudinger reaction, is elaborated as a lab-on-a-molecule for the select...