- A Convenient Preparation of 5-Iodo-1,4-disubstituted-1,2,3-triazole: Multicomponent One-Pot Reaction of Azide and Alkyne Mediated by CuI-NBS.
[作者：Li, Lingjun;Zhang, Guisheng;Zhu, Anlian;Zhang, Lihe;,期刊：Journal of Organic Chemistry, 页码：3630-3633 , 文章类型： 研究论文，,卷期：2008年73-9]
- The system of CuI and NBS was found to provide both I+ and Cu+ for the first time. An efficient method for prepn. of 5-iodo-1,4-disubstituted-1,2,3-triazole, e.g. I, was achieved by multicomponent one-pot reaction of az...
- Chiron Approach to the Synthesis of (2S,3R)-3-Hydroxypipecolic Acid and (2R,3R)-3-Hydroxy-2-hydroxymethylpiperidine from D-Glucose.
[作者：Kalamkar, Navnath B.;Kasture, Vijay M.;Dhavale, Dilip D.;,期刊：Journal of Organic Chemistry, 页码：3619-3622 , 文章类型： 研究论文，,卷期：2008年73-9]
- The first chiron approach from D-glucose for the total synthesis of (2S,3R)-3-hydroxypipecolic acid (-)-I (R = CO2H) and (2R,3R)-3-hydroxy-2-hydroxymethylpiperidine (-)-I (R = CH2OH) is reported. The synthetic pathway i...
- Synthesis of 2-(Pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, 2-(Pyridin-3-yl)-1-azabicyclo[2.2.2]octane, and 2-(Pyridin-3-yl)-1-azabicyclo[3.2.1]octane, a Class of Potent Nicotinic Acetylcholine Receptor-Ligands.
[作者：Bhatti, Balwinder S.;Strachan, Jon-Paul;Breining, Scott R.;Miller, Craig H.;Tahiri, Persida;Crooks, Peter A.;Deo, Niranjan;Day, Cynthia S.;Caldwell, William S.;,期刊：Journal of Organic Chemistry, 页码：3497-3507 , 文章类型： 研究论文，,卷期：2008年73-9]
- (Heterocyclic Compounds (One Hetero Atom)) Section In an attempt to generate nicotinic acetylcholine receptor (nAChR) ligands selective for the a4b2 and a7 subtype receptors we designed and synthesized constrained versio...
- Electrophilic ipso-Iodocyclization of N-(4-Methylphenyl)propiolamides: Selective Synthesis of 8-Methyleneazaspiro[4,5]trienes.
[作者：Yu, Quan-Fu;Zhang, Yue-Hua;Yin, Qin;Tang, Bo-Xiao;Tang, Ri-Yuan;Zhong, Ping;Li, Jin-Heng;,期刊：Journal of Organic Chemistry, 页码：3658-3661 , 文章类型： 研究论文，,卷期：2008年73-9]
- A novel and selective method for the synthesis of 8-methylenespiro[4,5]trienes via intramol. electrophilic ipso-iodocyclization of N-(4-methylphenyl)propiolamides has been developed. In the presence of ICl or I2, 8-meth...
- Palladium-Catalyzed Cyclization/Heck- and Cyclization/Conjugate-Addition-Type Sequences in the Preparation of Polysubstituted Furans.
[作者：Aurrecoechea, Jose M.;Durana, Aritz;Perez, Elena;,期刊：Journal of Organic Chemistry, 页码：3650-3653 , 文章类型： 研究论文，,卷期：2008年73-9]
- Palladium-catalyzed heterocyclization-coupling sequences have been developed starting from buta-1,2,3-trienyl carbinols, e.g., I, and electron-deficient alkenes. Polysubstituted furans are formed where the heterocyclic ...
- Total Synthesis of (?-Hyphodermins A and D.
[作者：Loughlin, Wendy A.;Jenkins, Ian D.;Henderson, Luke C.;Campitelli, Marc R.;Healy, Peter C.;,期刊：Journal of Organic Chemistry, 页码：3435-3440 , 文章类型： 研究论文，,卷期：2008年73-9]
- An efficient formal synthesis of (?-hyphodermins A I (R = OH) and D I (R = MeO), metabolites of Hyphoderma radula, has been completed in 12 and 11 steps, resp. The tricyclic carbon skeleton of enone II was rapidly assem...
- Total Synthesis of Cruentaren B.
[作者：Chakraborty, Tushar Kanti;Chattopadhyay, Amit Kumar;,期刊：Journal of Organic Chemistry, 页码：3578-3581 , 文章类型： 研究论文，,卷期：2008年73-9]
- A convergent total synthesis of the cytotoxic natural product cruentaren B (I) is completed in 26 steps (longest linear sequence) with an overall yield of 7.1%. For the construction of the C1-C11 benzolactone fragment o...
- Selective Synthesis of 4-Alkylidene-b-lactams and N,N'-Diarylamidines from Azides and Aryloxyacetyl Chlorides via a Ketenimine-Participating One-Pot Cascade Process.
[作者：Yang, Yun-Yun;Shou, Wang-Ge;Hong, Deng;Wang, Yan-Guang;,期刊：Journal of Organic Chemistry, 页码：3574-3577 , 文章类型： 研究论文，,卷期：2008年73-9]
- (Biomolecules and Their Synthetic Analogs) Section A one-pot cascade approach to 4-alkylidene-b-lactams and N,N'-diarylamidines from aryl azides and aryloxyacetyl chlorides has been developed. The chem. outcome of the r...
- An Expedient Synthesis of the Fibril Binding Compound FSB via Sequential Pd-Catalyzed Coupling Reactions.
[作者：Mantel, Mette Louise H.;Soebjerg, Lina S.;Huynh, Tri H. V.;Ebran, Jean-Philippe;Lindhardt, Anders T.;Nielsen, Niels C.;Skrydstrup, Troels;,期刊：Journal of Organic Chemistry, 页码：3570-3573 , 文章类型： 研究论文，,卷期：2008年73-9]
- The styryl benzene deriv. (E,E)-1-fluoro-2,5-bis(3-carboxy-4-hydroxy)styrylbenzene (FSB), well-known for its binding to b-amyloid peptide fibrils, was synthesized in an efficient manner exploiting two sequential Pd(0)-ca...
- An Efficient Protocol for the Enantioselective Preparation of a Key Polyfunctionalized Cyclohexane. New Access to (R)- and (S)-4-Hydroxy-2-cyclohexenone and (R)- and (S)-trans-Cyclohex-2-ene-1,4-diol.
[作者：Bayon, Pau;Marjanet, Georgina;Toribio, Gladis;Alibes, Ramon;de March, Pere;Figueredo, Marta;Font, Josep;,期刊：Journal of Organic Chemistry, 页码：3486-3491 , 文章类型： 研究论文，,卷期：2008年73-9]
- Starting from very accessible raw materials, such as p-methoxyphenol, ethylene glycol, and thiophenol, a protocol was developed to prep. multigram quantities of the polyfunctionalized cyclohexenone ketal I. A highly eff...
- An Efficient 1,2-Chelation-Controlled Reduction of Protected Hydroxy Ketones via Red-Al.
[作者：Bajwa, Naval;Jennings, Michael P.;,期刊：Journal of Organic Chemistry, 页码：3638-3641 , 文章类型： 研究论文，,卷期：2008年73-9]
- In this paper, Red-Al was demonstrated to be an efficient chelation-controlled reducing reagent for acyclic acetal-protected a-hydroxy ketones R1CH(OR2)COR3 (R1, R3 = n-Pr, Ph, PhCYC, PhCH:CH, PhCH2CH2, etc.; R2 = MeOCH2...
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