- Novel 4-(4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as D8-D7 Sterol Isomerase (Emopamil Binding Protein) Selective Ligands with Antiproliferative Activity.
[作者:Berardi, Francesco;Abate, Carmen;Ferorelli, Savina;de Robertis, Anna F.;Leopoldo, Marcello;Colabufo, Nicola A.;Niso, Mauro;Perrone, Roberto;,期刊:Journal of Medicinal Chemistry, 页码:7523-7531 , 文章类型: 研究论文,,卷期:2008年51-23]
- arylpiperazines previously studied and structurally related to some s receptors ligands were preliminarily screened. Consequently, a novel series of 2- or 2,6-disubstituted (CH3, CH3O, Cl, F) cis- and trans-4-(4-aryl)cy...
- Discovery of New Inhibitors of D-Alanine:D-Alanine Ligase by Structure-Based Virtual Screening.
[作者:Kovac, Andreja;Konc, Janez;Vehar, Blaz;Bostock, Julieanne M.;Chopra, Ian;Janezic, Dusanka;Gobec, Stanislav;,期刊:Journal of Medicinal Chemistry, 页码:7442-7448 , 文章类型: 研究论文,,卷期:2008年51-23]
- UDPMurNAc-pentapeptide is a crucial building block involved in peptidoglycan crosslinking. It is synthesized in the bacterial cytoplasm by the enzyme D-alanine:D-alanine ligase (Ddl). Structure-based virtual screening ...
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