We have investigated the site-specific backbone dynamics of mature amyloid beta (A beta) fibrils using solid-state NMR spectroscopy. Overall, the known beta-sheet segments and the turn linking these two beta-strands exhi...
The human genome encodes six isoforms of importin alpha that show greater than 60% sequence similarity and remarkable substrate specificity. The isoform importin alpha 5 can bind phosphorylated cargos such as STAT1 and E...