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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共79条记录   Activation of Intracellular Metabotropic Glutamate Receptor 5 in Striatal Neurons Leads to Up-regulation of Genes Associated with Sustained Synaptic Transmission Including Arc/Arg3.1 Protein [作者：Kumar, V; Fahey, PG; Jong, YJI; Ramanan, N; O'Malley, KL,期刊：Journal of Biological Chemistry, 页码：5412-5425 , 文章类型： Article，,卷期：2012年287-8] The G-protein coupled receptor, metabotropic glutamate receptor 5 (mGluR5), is expressed on both cell surface and intracellular membranes in striatal neurons. Using pharmacological tools to differentiate membrane respons... Roles of STAT3 and ZEB1 Proteins in E-cadherin Down-regulation and Human Colorectal Cancer Epithelial-Mesenchymal Transition [作者：Xiong, H; Hong, J; Du, W; Lin, YW; Ren, LL; Wang, YC; Su, WY; Wang, JL; Cui, Y; Wang, ZH; Fang, JY,期刊：Journal of Biological Chemistry, 页码：5819-5832 , 文章类型： Article，,卷期：2012年287-8] The progression of colorectal carcinoma (CRC) to invasive and metastatic disease may involve localized occurrences of epithelial-mesenchymal transition (EMT). However, mechanisms of the EMT process in CRC progression are... Acclimation of Chlamydomonas reinhardtii to Different Growth Irradiances [作者：Bonente, G; Pippa, S; Castellano, S; Bassi, R; Ballottari, M,期刊：Journal of Biological Chemistry, 页码：5833-5847 , 文章类型： Article，,卷期：2012年287-8] We report on the changes the photosynthetic apparatus of Chlamydomonas reinhardtii undergoes upon acclimation to different light intensity. When grown in high light, cells had a faster growth rate and higher biomass prod... Biochemical Analysis of Matrix Metalloproteinase Activation of Chemokines CCL15 and CCL23 and Increased Glycosaminoglycan Binding of CCL16 [作者：Starr, AE; Dufour, A; Maier, J; Overall, CM,期刊：Journal of Biological Chemistry, 页码：5848-5860 , 文章类型： Article，,卷期：2012年287-8] Leukocyte migration and activation is orchestrated by chemokines, the cleavage of which modulates their activity and glycosaminoglycan binding and thus their roles in inflammation and immunity. Early research identified ... Catalytic Mechanism of Sep-tRNA:Cys-tRNA Synthase SULFUR TRANSFER IS MEDIATED BY DISULFIDE AND PERSULFIDE [作者：Liu, YC; Dos Santos, PC; Zhu, X; Orlando, R; Dean, DR; Soll, D; Yuan, J,期刊：Journal of Biological Chemistry, 页码：5426-5433 , 文章类型： Article，,卷期：2012年287-8] Sep-tRNA: Cys-tRNA synthase (SepCysS) catalyzes the sulfhydrylation of tRNA-boundO-phosphoserine (Sep) to form cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) in methanogens that lack the canonical cysteinyl-tRNA synthetase (CysRS).... REF4 and RFR1, Subunits of the Transcriptional Coregulatory Complex Mediator, Are Required for Phenylpropanoid Homeostasis in Arabidopsis [作者：Bonawitz, ND; Soltau, WL; Blatchley, MR; Powers, BL; Hurlock, AK; Seals, LA; Weng, JK; Stout, J; Chapple, C,期刊：Journal of Biological Chemistry, 页码：5434-5445 , 文章类型： Article，,卷期：2012年287-8] The plant phenylpropanoid pathway produces an array of metabolites that impact human health and the utility of feed and fiber crops. We previously characterized several Arabidopsis thaliana mutants with dominant mutation... Regulation of the Ste20-like Kinase, SLK INVOLVEMENT OF ACTIVATION SEGMENT PHOSPHORYLATION [作者：Luhovy, AY; Jaberi, A; Papillon, J; Guillemette, J; Cybulsky, AV,期刊：Journal of Biological Chemistry, 页码：5446-5458 , 文章类型： Article，,卷期：2012年287-8] Expression and activation of the Ste20-like kinase, SLK, is increased during kidney development and recovery from ischemic acute kidney injury. SLK promotes apoptosis, and it may regulate cell survival during injury or r... YajL, Prokaryotic Homolog of Parkinsonism-associated Protein DJ-1, Functions as a Covalent Chaperone for Thiol Proteome [作者：Le, HT; Gautier, V; Kthiri, F; Malki, A; Messaoudi, N; Mihoub, M; Landoulsi, A; An, YJ; Cha, SS; Richarme, G,期刊：Journal of Biological Chemistry, 页码：5861-5870 , 文章类型： Article，,卷期：2012年287-8] YajL is the closest Escherichia coli homolog of the Parkinsonism-associated protein DJ-1, a multifunctional oxidative stress response protein whose biochemical function remains unclear. We recently reported the aggregati... Protein Kinase D1 Is Essential for Contraction-induced Glucose Uptake but Is Not Involved in Fatty Acid Uptake into Cardiomyocytes [作者：Dirkx, E; Schwenk, RW; Coumans, WA; Hoebers, N; Angin, Y; Viollet, B; Bonen, A; van Eys, GJJM; Glatz, JFC; Luiken, JJFP,期刊：Journal of Biological Chemistry, 页码：5871-5881 , 文章类型： Article，,卷期：2012年287-8] Increased contraction enhances substrate uptake into cardiomyocytes via translocation of the glucose transporter GLUT4 and the long chain fatty acid (LCFA) transporter CD36 from intracellular stores to the sarcolemma. Ad... Assembly and Architecture of Biogenesis of Lysosome-related Organelles Complex-1 (BLOC-1) [作者：Lee, HH; Nemecek, D; Schindler, C; Smith, WJ; Ghirlando, R; Steven, AC; Bonifacino, JS; Hurley, JH,期刊：Journal of Biological Chemistry, 页码：5882-5890 , 文章类型： Article，,卷期：2012年287-8] BLOC-1 (biogenesis of lysosome-related organelles complex-1) is critical for melanosome biogenesis and has also been implicated in neurological function and disease. We show that BLOC-1 is an elongated complex that conta... Direct Binding of Specific AUF1 Isoforms to Tandem Zinc Finger Domains of Tristetraprolin (TTP) Family Proteins [作者：Kedar, VP; Zucconi, BE; Wilson, GM; Blackshear, PJ,期刊：Journal of Biological Chemistry, 页码：5459-5471 , 文章类型： Article，,卷期：2012年287-8] Tristetraprolin (TTP) is the prototype of a family of CCCH tandem zinc finger proteins that can bind to AU-rich elements in mRNAs and promote their decay. TTP binds to mRNA through its central tandem zinc finger domain; ... RNA Chaperone Activity of Human La Protein Is Mediated by Variant RNA Recognition Motif [作者：Naeeni, AR; Conte, MR; Bayfield, MA,期刊：Journal of Biological Chemistry, 页码：5472-5482 , 文章类型： Article，,卷期：2012年287-8] La proteins are conserved factors in eukaryotes that bind and protect the 3' trailers of pre-tRNAs from exonuclease digestion via sequence-specific recognition of UUU-3'OH. La has also been hypothesized to assist pre-tRN... Mechanism of MTA1 Protein Overexpression-linked Invasion MTA1 REGULATION OF HYALURONAN-MEDIATED MOTILITY RECEPTOR (HMMR) EXPRESSION AND FUNCTION [作者：Sankaran, D; Pakala, SB; Nair, VS; Sirigiri, DNR; Cyanam, D; Ha, NH; Li, DQ; Santhoshkumar, TR; Pillai, MR; Kumar, R,期刊：Journal of Biological Chemistry, 页码：5483-5491 , 文章类型： Article，,卷期：2012年287-8] Even though the hyaluronan-mediated motility receptor (HMMR), a cell surface oncogenic protein, is widely up-regulated in human cancers and correlates well with cell motility and invasion, the underlying molecular and na... Decorin Antagonizes the Angiogenic Network CONCURRENT INHIBITION OF MET, HYPOXIA INDUCIBLE FACTOR 1 alpha, VASCULAR ENDOTHELIAL GROWTH FACTOR A, AND INDUCTION OF THROMBOSPONDIN-1 AND TIMP3 [作者：Neill, T; Painter, H; Buraschi, S; Owens, RT; Lisanti, MP; Schaefer, L; Iozzo, RV,期刊：Journal of Biological Chemistry, 页码：5492-5506 , 文章类型： Article，,卷期：2012年287-8] Decorin, a small leucine-rich proteoglycan, inhibits tumor growth by antagonizing multiple receptor tyrosine kinases including EGFR and Met. Here, we investigated decorin during normoxic angiogenic signaling. An angiogen... Engineering Upper Hinge Improves Stability and Effector Function of a Human IgG1 [作者：Yan, BX; Boyd, D; Kaschak, T; Tsukuda, J; Shen, A; Lin, YW; Chung, S; Gupta, P; Kamath, A; Wong, A; Vernes, JM; Meng, GY; Totpal, K; Schaefer, G; Jiang, GY; Nogal, B; Emery, C; Vanderlaan, M; Carter, P; Harris, R; Amanullah, A,期刊：Journal of Biological Chemistry, 页码：5891-5897 , 文章类型： Article，,卷期：2012年287-8] Upper hinge is vulnerable to radical attacks that result in breakage of the heavy-light chain linkage and cleavage of the hinge of an IgG1. To further explore mechanisms responsible for the radical induced hinge degradat... Glypican-1 Stimulates Skp2 Autoinduction Loop and G(1)/S Transition in Endothelial Cells [作者：Qiao, DH; Meyer, K; Friedl, A,期刊：Journal of Biological Chemistry, 页码：5898-5909 , 文章类型： Article，,卷期：2012年287-8] The heparan sulfate proteoglycan glypican-1 (GPC1) is involved in tumorigenesis and angiogenesis and is overexpressed frequently in tumor and endothelial cells (ECs) in human gliomas. We demonstrated previously that in b...