- Phosphatidylinositol 4-Kinase III beta Is Required for Severe Acute Respiratory Syndrome Coronavirus Spike-mediated Cell Entry
[作者:Yang, N; Ma, P; Lang, JS; Zhang, YL; Deng, JJ; Ju, XW; Zhang, GY; Jiang, CY,期刊:Journal of Biological Chemistry, 页码:8457-8467 , 文章类型: Article,,卷期:2012年287-11]
- Phosphatidylinositol kinases (PI kinases) play an important role in the life cycle of several viruses after infection. Using gene knockdown technology, we demonstrate that phosphatidylinositol 4-kinase III beta (PI4KB) i...
- Classically Activated Macrophages Use Stable Microtubules for Matrix Metalloproteinase-9 (MMP-9) Secretion
[作者:Hanania, R; Sun, HS; Xu, KW; Pustylnik, S; Jeganathan, S; Harrison, RE,期刊:Journal of Biological Chemistry, 页码:8468-8483 , 文章类型: Article,,卷期:2012年287-11]
- As major effector cells of the innate immune response, macrophages must adeptly migrate from blood to infected tissues. Endothelial transmigration is accomplished by matrix metalloproteinase (MMP)-induced degradation of ...
- Trimeric, Coiled-coil Extension on Peptide Fusion Inhibitor of HIV-1 Influences Selection of Resistance Pathways
[作者:Zhuang, M; Wang, W; De Feo, CJ; Vassell, R; Weiss, CD,期刊:Journal of Biological Chemistry, 页码:8297-8309 , 文章类型: Article,,卷期:2012年287-11]
- Peptides corresponding to N- and C-terminal heptad repeat regions (HR1 and HR2, respectively) of viral fusion proteins can block infection of viruses in a dominant negative manner by interfering with refolding of the vir...
- Involvement of Stress Kinase Mitogen-activated Protein Kinase Kinase 7 in Regulation of Mammalian Circadian Clock
[作者:Uchida, Y; Osaki, T; Yamasaki, T; Shimomura, T; Hata, S; Horikawa, K; Shibata, S; Todo, T; Hirayama, J; Nishina, H,期刊:Journal of Biological Chemistry, 页码:8318-8326 , 文章类型: Article,,卷期:2012年287-11]
- The stress kinase mitogen-activated protein kinase kinase 7 (MKK7) is a specific activator of c-Jun N-terminal kinase (JNK), which controls various physiological processes, such as cell proliferation, apoptosis, differen...
- Caenorhabditis elegans RNA-processing Protein TDP-1 Regulates Protein Homeostasis and Life Span
[作者:Zhang, T; Hwang, HY; Hao, HP; Talbot, C; Wang, JO,期刊:Journal of Biological Chemistry, 页码:8371-8382 , 文章类型: Article,,卷期:2012年287-11]
- Transactive response DNA-binding protein (TARDBP/TDP-43), a heterogeneous nuclear ribonucleoprotein (hnRNP) with diverse activities, is a common denominator in several neurodegenerative disorders, including amyotrophic l...
- Identification of novel Ssl0352 protein (NdhS), essential for efficient operation of cyclic electron transport around photosystem I, in NADPH: plastoquinone oxidoreductase (NDH-1) complexes of Synechocystis sp. PCC 6803. (vol 286, pg 36992, 2011)
[作者:Battchikova, N; Wei, LZ; Du, LY; Bersanini, L; Aro, EM; Ma, WM,期刊:Journal of Biological Chemistry, 页码:8660-8660 , 文章类型: Correction,,卷期:2012年287-11]
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- Leptin-induced Epithelial-Mesenchymal Transition in Breast Cancer Cells Requires beta-Catenin Activation via Akt/GSK3- and MTA1/Wnt1 Protein-dependent Pathways
[作者:Yan, D; Avtanski, D; Saxena, NK; Sharma, D,期刊:Journal of Biological Chemistry, 页码:8598-8612 , 文章类型: Article,,卷期:2012年287-11]
- Perturbations in the adipocytokine profile, especially higher levels of leptin, are a major cause of breast tumor progression and metastasis; the underlying mechanisms, however, are not well understood. In particular, it...
- Ssu72 Phosphatase-dependent Erasure of Phospho-Ser7 Marks on the RNA Polymerase II C-terminal Domain Is Essential for Viability and Transcription Termination
[作者:Zhang, DW; Mosley, AL; Ramisetty, SR; Rodriguez-Molina, JB; Washburn, MP; Ansari, AZ,期刊:Journal of Biological Chemistry, 页码:8541-8551 , 文章类型: Article,,卷期:2012年287-11]
- The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) serves an important role in coordinating stage-specific recruitment and release of cellular machines during transcription. Dynamic placemen...
- O-antigen and Core Carbohydrate of Vibrio fischeri Lipopolysaccharide COMPOSITION AND ANALYSIS OF THEIR ROLE IN EUPRYMNA SCOLOPES LIGHT ORGAN COLONIZATION
[作者:Post, DMB; Yu, LP; Krasity, BC; Choudhury, B; Mandel, MJ; Brennan, CA; Ruby, EG; McFall-Ngai, MJ; Gibson, BW; Apicella, MA,期刊:Journal of Biological Chemistry, 页码:8515-8530 , 文章类型: Article,,卷期:2012年287-11]
- Vibrio fischeri exists in a symbiotic relationship with the Hawaiian bobtail squid, Euprymna scolopes, where the squid provides a home for the bacteria, and the bacteria in turn provide camouflage that helps protect the ...
- Structural Insight into Recognition of Methylated Histone Tails by Retinoblastoma-binding Protein 1
[作者:Gong, WB; Zhou, T; Mo, JJ; Perrett, S; Wang, JF; Feng, YG,期刊:Journal of Biological Chemistry, 页码:8531-8540 , 文章类型: Article,,卷期:2012年287-11]
- Retinoblastoma-binding protein 1 (RBBP1), also named AT-rich interaction domain containing 4A (ARID4A), is a tumor and leukemia suppressor involved in epigenetic regulation in leukemia and Prader-Willi/Angelman syndromes...
- Mislocalization of Fukutin Protein by Disease-causing Missense Mutations Can Be Rescued with Treatments Directed at Folding Amelioration
[作者:Tachikawa, M; Kanagawa, M; Yu, CC; Kobayashi, K; Toda, T,期刊:Journal of Biological Chemistry, 页码:8398-8406 , 文章类型: Article,,卷期:2012年287-11]
- Fukuyama-type congenital muscular dystrophy (FCMD), the second most common childhood muscular dystrophy in Japan, is caused by alterations in the fukutin gene. Mutations in fukutin cause abnormal glycosylation of alpha-d...
- High Throughput Engineering to Revitalize a Vestigial Electron Transfer Pathway in Bacterial Photosynthetic Reaction Centers
[作者:Faries, KM; Kressel, LL; Wander, MJ; Holten, D; Laible, PD; Kirmaier, C; Hanson, DK,期刊:Journal of Biological Chemistry, 页码:8507-8514 , 文章类型: Article,,卷期:2012年287-11]
- Photosynthetic reaction centers convert light energy into chemical energy in a series of transmembrane electron transfer reactions, each with near 100% yield. The structures of reaction centers reveal two symmetry-relate...
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