- Luminal and Cytosolic pH Feedback on Proton Pump Activity and ATP Affinity of V-type ATPase from Arabidopsis
[作者:Rienmuller, F; Dreyer, I; Schonknecht, G; Schulz, A; Schumacher, K; Nagy, R; Martinoia, E; Marten, I; Hedrich, R,期刊:Journal of Biological Chemistry, 页码:8986-8993 , 文章类型: Article,,卷期:2012年287-12]
- Proton pumping of the vacuolar-type H+-ATPase into the lumen of the central plant organelle generates a proton gradient of often 1-2 pH units or more. Although structural aspects of the V-type ATPase have been studied in...
- Antibody-induced Enhancement of Factor VIIa Activity through Distinct Allosteric Pathways
[作者:Andersen, LM; Andreasen, PA; Svendsen, I; Keemink, J; Ostergaard, H; Persson, E,期刊:Journal of Biological Chemistry, 页码:8994-9001 , 文章类型: Article,,卷期:2012年287-12]
- In the absence of its cofactor tissue factor (TF), coagulation factor VIIa (FVIIa) predominantly exists in a zymogen-like, catalytically incompetent state. Here we demonstrate that conformation-specific monoclonal antibo...
- Organ-specific Sulfation Patterns of Heparan Sulfate Generated by Extracellular Sulfatases Sulf1 and Sulf2 in Mice
[作者:Nagamine, S; Tamba, M; Ishimine, H; Araki, K; Shiomi, K; Okada, T; Ohto, T; Kunita, S; Takahashi, S; Wismans, RGP; van Kuppevelt, TH; Masu, M; Keino-Masu, K,期刊:Journal of Biological Chemistry, 页码:9579-9590 , 文章类型: Article,,卷期:2012年287-12]
- Heparan sulfate endosulfatases Sulf1 and Sulf2 hydrolyze 6-O-sulfate in heparan sulfate, thereby regulating cellular signaling. Previous studies have revealed that Sulfs act predominantly on UA2S-GlcNS6S disaccharides an...
- Role of Receptor-attached Phosphates in Binding of Visual and Non-visual Arrestins to G Protein-coupled Receptors
[作者:Gimenez, LE; Kook, S; Vishnivetskiy, SA; Ahmed, MR; Gurevich, EV; Gurevich, VV,期刊:Journal of Biological Chemistry, 页码:9028-9040 , 文章类型: Article,,卷期:2012年287-12]
- Arrestins are a small family of proteins that regulate G protein-coupled receptors (GPCRs). Arrestins specifically bind to phosphorylated active receptors, terminating G protein coupling, targeting receptors to endocytic...
- Crystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic Fungus Aspergillus fumigatus
[作者:Dhatwalia, R; Singh, H; Oppenheimer, M; Karr, DB; Nix, JC; Sobrado, P; Tanner, JJ,期刊:Journal of Biological Chemistry, 页码:9041-9051 , 文章类型: Article,,卷期:2012年287-12]
- UDP-galactopyranose mutase (UGM) is a flavoenzyme that catalyzes the conversion of UDP-galactopyranose to UDP-galactofuranose, which is a central reaction in galactofuranose biosynthesis. Galactofuranose has never been f...
- Heme Utilization in the Caenorhabditis elegans Hypodermal Cells Is Facilitated by Heme-responsive Gene-2
[作者:Chen, CY; Samuel, TK; Krause, M; Dailey, HA; Hamza, I,期刊:Journal of Biological Chemistry, 页码:9601-9612 , 文章类型: Article,,卷期:2012年287-12]
- The roundworm Caenorhabditis elegans is a heme auxotroph that requires the coordinated actions of HRG-1 heme permeases to transport environmental heme into the intestine and HRG-3, a secreted protein, to deliver intestin...
- The Vital Role of Polymerase zeta and REV1 in Mutagenic, but Not Correct, DNA Synthesis across Benzo[a]pyrene-dG and Recruitment of Polymerase zeta by REV1 to Replication-stalled Site
[作者:Hashimoto, K; Cho, YJ; Yang, IY; Akagi, J; Ohashi, E; Tateishi, S; de Wind, N; Hanaoka, F; Ohmori, H; Moriya, M,期刊:Journal of Biological Chemistry, 页码:9613-9622 , 文章类型: Article,,卷期:2012年287-12]
- The DNA synthesis across DNA lesions, termed translesion synthesis (TLS), is a complex process influenced by various factors. To investigate this process in mammalian cells, we examined TLS across a benzo[a] pyrene dihyd...
- Characterization of the Arabinogalactan Protein 31 (AGP31) of Arabidopsis thaliana NEW ADVANCES ON THE HYP-O-GLYCOSYLATION OF THE PRO-RICH DOMAIN
[作者:Hijazi, M; Durand, J; Pichereaux, C; Pont, F; Jamet, E; Albenne, C,期刊:Journal of Biological Chemistry, 页码:9623-9632 , 文章类型: Article,,卷期:2012年287-12]
- Proteins are important actors in plant cell walls because they contribute to their architecture and their dynamics. Among them, hydroxyproline (Hyp)-rich glycoproteins constitute a complex family of O-glycoproteins with ...
- Internalization of Proprotein Convertase PC7 from Plasma Membrane Is Mediated by a Novel Motif
[作者:Declercq, J; Meulemans, S; Plets, E; Creemers, JWM,期刊:Journal of Biological Chemistry, 页码:9052-9060 , 文章类型: Article,,卷期:2012年287-12]
- Proprotein convertase 7 (PC7) is a member of the subtilisin-like proprotein convertase family, which is involved in the endoproteolysis of a variety of precursor proteins. Under steady state conditions, PC7 is mainly loc...
- Short Chain Dehydrogenase/Reductase Rdhe2 Is a Novel Retinol Dehydrogenase Essential for Frog Embryonic Development
[作者:Belyaeva, OV; Lee, SA; Adams, MK; Chang, CB; Kedishvili, NY,期刊:Journal of Biological Chemistry, 页码:9061-9071 , 文章类型: Article,,卷期:2012年287-12]
- The enzymes responsible for the rate-limiting step in retinoic acid biosynthesis, the oxidation of retinol to retinaldehyde, during embryogenesis and in adulthood have not been fully defined. Here, we report that a novel...
- Solution Structure of Homology Region (HR) Domain of Type II Secretion System
[作者:Gu, S; Kelly, G; Wang, XH; Frenkiel, T; Shevchik, VE; Pickersgill, RW,期刊:Journal of Biological Chemistry, 页码:9072-9080 , 文章类型: Article,,卷期:2012年287-12]
- The type II secretion system of Gram-negative bacteria is important for bacterial pathogenesis and survival; it is composed of 12 mostly multimeric core proteins, which build a sophisticated secretion machine spanning bo...
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