- Insulin Promotes Neuronal Survival via the Alternatively Spliced Protein Kinase C delta II Isoform
[作者:Apostolatos, A; Song, SJ; Acosta, S; Peart, M; Watson, JE; Bickford, P; Cooper, DR; Patel, NA,期刊:Journal of Biological Chemistry, 页码:9299-9310 , 文章类型: Article,,卷期:2012年287-12]
- Insulin signaling pathways in the brain regulate food uptake and memory and learning. Insulin and protein kinase C (PKC) pathways are integrated and function closely together. PKC activation in the brain is essential for...
- Platelet-activating Factor Receptor Agonists Mediate Xeroderma Pigmentosum A Photosensitivity
[作者:Yao, YX; Harrison, KA; Al-Hassani, M; Murphy, RC; Rezania, S; Konger, RL; Travers, JB,期刊:Journal of Biological Chemistry, 页码:9311-9321 , 文章类型: Article,,卷期:2012年287-12]
- To date, oxidized glycerophosphocholines (Ox-GPCs) with platelet-activating factor (PAF) activity produced non-enzymatically have not been definitively demonstrated to mediate any known disease processes. Here we provide...
- InvA protein is a Nudix hydrolase required for infection by pathogenic Leptospira in cell lines and animals (vol 286, pg 36852, 2011)
[作者:Luo, YH; Liu, Y; Sun, D; Ojcius, DM; Zhao, JF; Lin, X; Wu, D; Zhang, RG; Chen, M; Li, LJ; Yan, J,期刊:Journal of Biological Chemistry, 页码:9327-9327 , 文章类型: Correction,,卷期:2012年287-12]
-
- RamA, a protein required for reductive activation of corrinoid-dependent methylamine methyltransferase reactions in methanogenic Archaea (vol 284, pg 2285, 2009)
[作者:Ferguson, T; Soares, JA; Lienard, T; Gottschalk, G; Krzycki, JA,期刊:Journal of Biological Chemistry, 页码:9328-9328 , 文章类型: Correction,,卷期:2012年287-12]
-
- Diversity in the C3b contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family (vol 287, pg 628, 2012)
[作者:Garcia, BL; Summers, BJ; Lin, ZE; Ramyar, KX; Ricklin, D; Kamath, DV; Fu, ZQ; Lambris, JD; Geisbrecht, BV,期刊:Journal of Biological Chemistry, 页码:9329-9329 , 文章类型: Correction,,卷期:2012年287-12]
-
- Function of Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4) as a Mechanical Transducer in Flow-sensitive Segments of Renal Collecting Duct System
[作者:Berrout, J; Jin, M; Mamenko, M; Zaika, O; Pochynyuk, O; O'Neil, RG,期刊:Journal of Biological Chemistry, 页码:8782-8791 , 文章类型: Article,,卷期:2012年287-12]
- The TRPV4 Ca2+-permeable channel is sensitive to mechanical stimuli. In the current study we have employed immunocytochemical staining in kidney slices and functional assessments (Ca2+ imaging) in isolated, split-opened,...
- High Throughput Screening against the Peroxidase Cascade of African Trypanosomes Identifies Antiparasitic Compounds That Inactivate Tryparedoxin
[作者:Fueller, F; Jehle, B; Putzker, K; Lewis, JD; Krauth-Siegel, RL,期刊:Journal of Biological Chemistry, 页码:8792-8802 , 文章类型: Article,,卷期:2012年287-12]
- In African trypanosomes, the detoxification of broad spectrum hydroperoxides relies on a unique cascade composed of trypanothione (T(SH)(2)), trypanothione reductase, tryparedoxin (Tpx), and nonselenium glutathione perox...
- Heat Shock Protein 90 alpha (Hsp90 alpha) Is Phosphorylated in Response to DNA Damage and Accumulates in Repair Foci
[作者:Quanz, M; Herbette, A; Sayarath, M; de Koning, L; Dubois, T; Sun, JS; Dutreix, M,期刊:Journal of Biological Chemistry, 页码:8803-8815 , 文章类型: Article,,卷期:2012年287-12]
- DNA damage triggers a complex signaling cascade involving a multitude of phosphorylation events. We found that the threonine 7 (Thr-7) residue of heat shock protein 90 alpha (Hsp90 alpha) was phosphorylated immediately a...
- tRNA-controlled Nuclear Import of a Human tRNA Synthetase
[作者:Fu, GS; Xu, T; Shi, Y; Wei, N; Yang, XL,期刊:Journal of Biological Chemistry, 页码:9330-9334 , 文章类型: Article,,卷期:2012年287-12]
- Aminoacyl-tRNA synthetases, essential components of the cytoplasmic translation apparatus, also have nuclear functions that continue to be elucidated. However, little is known about how the distribution between cytoplasm...
- Structural Basis for Ca2+-induced Activation and Dimerization of Estrogen Receptor alpha by Calmodulin
[作者:Zhang, YH; Li, ZG; Sacks, DB; Ames, JB,期刊:Journal of Biological Chemistry, 页码:9336-9344 , 文章类型: Article,,卷期:2012年287-12]
- The estrogen receptor alpha (ER-alpha) regulates expression of target genes implicated in development, metabolism, and breast cancer. Calcium-dependent regulation of ER-alpha is critical for activating gene expression an...
- Novel Role for Non-muscle Myosin Light Chain Kinase (MLCK) in Hyperoxia-induced Recruitment of Cytoskeletal Proteins, NADPH Oxidase Activation, and Reactive Oxygen Species Generation in Lung Endothelium
[作者:Usatyuk, PV; Singleton, PA; Pendyala, S; Kalari, SK; He, DH; Gorshkova, IA; Camp, SM; Moitra, J; Dudek, SM; Garcia, JGN; Natarajan, V,期刊:Journal of Biological Chemistry, 页码:9360-9375 , 文章类型: Article,,卷期:2012年287-12]
- We recently demonstrated that hyperoxia (HO) activates lung endothelial cell NADPH oxidase and generates reactive oxygen species(ROS)/superoxide via Src-dependent tyrosine phosphorylation of p47(phox) and cortactin. Here...
- Interleukin-22 Is Produced by Invariant Natural Killer T Lymphocytes during Influenza A Virus Infection POTENTIAL ROLE IN PROTECTION AGAINST LUNG EPITHELIAL DAMAGES
[作者:Paget, C; Ivanov, S; Fontaine, J; Renneson, J; Blanc, F; Pichavant, M; Dumoutier, L; Ryffel, B; Renauld, JC; Gosset, P; Gosset, P; Si-Tahar, M; Faveeuw, C; Trottein, F,期刊:Journal of Biological Chemistry, 页码:8816-8829 , 文章类型: Article,,卷期:2012年287-12]
- Invariant natural killer T (iNKT) cells are non-conventional lipid-reactive alpha beta T lymphocytes that play a key role in host responses during viral infections, in particular through the swift production of cytokines...
- Dehydrodiconiferyl Alcohol Isolated from Cucurbita moschata Shows Anti-adipogenic and Anti-lipogenic Effects in 3T3-L1 Cells and Primary Mouse Embryonic Fibroblasts
[作者:Lee, J; Kim, D; Choi, J; Choi, H; Ryu, JH; Jeong, J; Park, EJ; Kim, SH; Kim, S,期刊:Journal of Biological Chemistry, 页码:8839-8851 , 文章类型: Article,,卷期:2012年287-12]
- A water-soluble extract from the stems of Cucurbita moschata, code named PG105, was previously found to contain strong anti-obesity activities in a high fat diet-induced obesity mouse model. One of its biological charact...
|