- Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: A potential treatment for lymphangioleiomyomatosis
[作者：Makovski, V; Haklai, R; Kloog, Y,期刊：International Journal of Cancer, 页码：1420-1429 , 文章类型： Article，,卷期：2012年130-6]
- The small GTPase proteins, Ras and Rheb, serve as molecular switches regulating cell proliferation, differentiation and apoptosis. Ras also regulates Rheb by inactivating the tuberous sclerosis complex (TSC), which inclu...
- Methylseleninic acid downregulates hypoxia-inducible factor-1a in invasive prostate cancer
[作者：Sinha, I; Null, K; Wolter, W; Suckow, MA; King, T; Pinto, JT; Sinha, R,期刊：International Journal of Cancer, 页码：1430-1439 , 文章类型： Article，,卷期：2012年130-6]
- Alternative strategies are needed to control growth of advanced and hormone refractory prostate cancer. In this regard, we investigated the efficacy of methylseleninic acid (MSeA), a penultimate precursor to the highly r...
- The novel DNA alkylating agent BO-1090 suppresses the growth of human oral cavity cancer in xenografted and orthotopic mouse models
[作者：Sanjiv, K; Su, TL; Suman, S; Kakadiya, R; Lai, TC; Wang, HY; Hsiao, M; Lee, TC,期刊：International Journal of Cancer, 页码：1440-1450 , 文章类型： Article，,卷期：2012年130-6]
- Oral cancer is the fourth-most common cause of death in males and overall the sixth-most common cause of cancer death in Taiwan. Surgery, radiotherapy and chemotherapy combined with other therapies are the most common tr...
- Smoking adversely affects survival in acute myeloid leukemia patients
[作者：Varadarajan, R; Licht, AS; Hyland, AJ; Ford, LA; Sait, SNJ; Block, AW; Barcos, M; Baer, MR; Wang, ES; Wetzler, M,期刊：International Journal of Cancer, 页码：1451-1458 , 文章类型： Article，,卷期：2012年130-6]
- Smoking adversely affects hematopoietic stem cell transplantation outcome. We asked whether smoking affected outcome of newly diagnosed acute myeloid leukemia (AML) patients treated with chemotherapy. Data were collected...
- A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells
[作者：Lin, L; Benson, DM; DeAngelis, S; Bakan, CE; Li, PK; Li, CL; Lin, JY,期刊：International Journal of Cancer, 页码：1459-1469 , 文章类型： Article，,卷期：2012年130-6]
- We characterized the effects of a newly developed signal transducers and activators of transcription 3 (STAT3) inhibitor, LLL12 in multiple myeloma (MM) cells. LLL12 specifically inhibited STAT3 phosphorylation, nuclear ...
- The toll-like receptor 2 (TLR2)-196 to-174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C
[作者：Nischalke, HD; Coenen, M; Berger, C; Aldenhoff, K; Muller, T; Berg, T; Kramer, B; Korner, C; Odenthal, M; Schulze, F; Grunhage, F; Nattermann, J; Sauerbruch, T; Spengler, U,期刊：International Journal of Cancer, 页码：1470-1475 , 文章类型： Article，,卷期：2012年130-6]
- Chronic hepatitis C virus (HCV) infection is a major risk factor for hepatocellular carcinoma (HCC). HCV proteins core and NS3 can bind to toll-like receptor 2 (TLR2) and trigger inflammatory responses. Polymorphisms in ...
- Cancer recurrence after surgery: Direct and indirect effects of anesthetic agents*
[作者：Tavare, AN; Perry, NJS; Benzonana, LL; Takata, M; Ma, DQ,期刊：International Journal of Cancer, 页码：1237-1250 , 文章类型： Review，,卷期：2012年130-6]
- Surgery is of paramount importance in the management of solid tumors as definitive resection can be totally curative. Nonetheless, metastatic recurrence after surgery remains a major cause of morbidity and mortality. Int...
- Regenerating islet-derived family member, 4 modulates multiple receptor tyrosine kinases and mediators of drug resistance in cancer
[作者：Vanderlaag, K; Wang, W; Fayadat-Dilman, L; Wagner, J; Bald, L; Grein, J; Janatpour, MJ,期刊：International Journal of Cancer, 页码：1251-1263 , 文章类型： Article，,卷期：2012年130-6]
- Regenerating islet-derived family member, 4 (Reg IV) is a secreted protein and member of the C-type lectin superfamily. Expression analyses have characterized Reg IV as a prognostic marker for certain cancers; however, t...
- Endothelin-1 stimulates colon cancer adjacent fibroblasts
[作者：Knowles, JP; Xu, SW; Haque, SU; Bhalla, A; Dashwood, MR; Yang, SY; Taylor, I; Winslet, MC; Abraham, DJ; Loizidou, M,期刊：International Journal of Cancer, 页码：1264-1272 , 文章类型： Article，,卷期：2012年130-6]
- Endothelin-1 (ET-1) is produced by and stimulates colorectal cancer cells. Fibroblasts produce tumour stroma required for cancer development. We investigated whether ET-1 stimulated processes involved in tumour stroma pr...
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