- Hepatitis C Virus Infects the Endothelial Cells of the Blood-Brain Barrier
[作者：Fletcher, NF; Wilson, GK; Murray, J; Hu, K; Lewis, A; Reynolds, GM; Stamataki, Z; Meredith, LW; Rowe, IA; Luo, GX; Lopez-Ramirez, MA; Baumert, TF; Weksler, B; Couraud, PO; Kim, KS; Romero, IA; Jopling, C; Morgello, S; Balfe, P; McKeating, JA,期刊：Gastroenterology, 页码：634-U326 , 文章类型： Article，,卷期：2012年142-3]
- BACKGROUND & AIMS: Hepatitis C virus (HCV) infection leads to progressive liver disease and is associated with a variety of extrahepatic syndromes, including central nervous system (CNS) abnormalities. However, it is unc...
- Autophagy Protects Cells From HCV-Induced Defects in Lipid Metabolism
[作者：Vescovo, T; Romagnoli, A; Perdomo, AB; Corazzari, M; Ciccosanti, F; Alonzi, T; Nardacci, R; Ippolito, G; Tripodi, M; Garcia-Monzon, C; Lo Iacono, O; Piacentini, M; Fimia, GM,期刊：Gastroenterology, 页码：644-U339 , 文章类型： Article，,卷期：2012年142-3]
- BACKGROUND & AIMS: Autophagy is a lysosome-mediated catabolic process that mediates degradation and recycling of all major components of eukaryotic cells. Different stresses, including viral and bacterial infection, indu...
- Peptidomimetic Escape Mechanisms Arise via Genetic Diversity in the Ligand-Binding Site of the Hepatitis C Virus NS3/4A Serine Protease
[作者：Welsch, C; Shimakami, T; Hartmann, C; Yang, Y; Domingues, FS; Lengauer, T; Zeuzem, S; Lemon, SM,期刊：Gastroenterology, 页码：654-663 , 文章类型： Article，,卷期：2012年142-3]
- BACKGROUND & AIMS: It is a challenge to develop direct-acting antiviral agents that target the nonstructural protein 3/4A protease of hepatitis C virus because resistant variants develop. Ketoamide compounds, designed to...
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