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  • Frequent Detection of Pancreatic Lesions in Asymptomatic High-Risk Individuals
    [作者:Canto, MI; Hruban, RH; Fishman, EK; Kamel, IR; Schulick, R; Zhang, Z; Topazian, M; Takahashi, N; Fletcher, J; Petersen, G; Klein, AP; Axilbund, J; Griffin, C; Syngal, S; Saltzman, JR; Mortele, KJ; Lee, J; Tamm, E; Vikram, R; Bhosale, P; Margolis, D; Farrell, J; Goggins, M,期刊:Gastroenterology, 页码:796-804 , 文章类型: Article,,卷期:2012年142-4]
  • BACKGROUND & AIMS: The risk of pancreatic cancer is increased in patients with a strong family history of pancreatic cancer or a predisposing germline mutation. Screening can detect curable, noninvasive pancreatic neopla...
  • RACK1 Suppresses Gastric Tumorigenesis by Stabilizing the beta-Catenin Destruction Complex
    [作者:Deng, YZ; Yao, F; Li, JJ; Mao, ZF; Hu, PT; Long, LY; Li, G; Ji, XD; Shi, S; Guan, DX; Feng, YY; Cui, L; Li, DS; Liu, Y; Du, X; Guo, MZ; Xu, LY; Li, EM; Wang, HY; Xie, D,期刊:Gastroenterology, 页码:812-U246 , 文章类型: Article,,卷期:2012年142-4]
  • BACKGROUND & AIMS: Dysregulation of Wnt signaling has been involved in gastric tumorigenesis by mechanisms that are not fully understood. The receptor for activated protein kinase C (RACK1, GNB2L1) is involved in develop...
  • Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells
    [作者:Almeida, MI; Nicoloso, MS; Zeng, LZ; Ivan, C; Spizzo, R; Gafa, R; Xiao, LC; Zhang, XN; Vannini, I; Fanini, F; Fabbri, M; Lanza, G; Reis, RM; Zweidler-McKay, PA; Calin, GA,期刊:Gastroenterology, 页码:886-U355 , 文章类型: Article,,卷期:2012年142-4]
  • BACKGROUND & AIMS: MicroRNAs (miRNAs) can promote or inhibit tumor growth and are therefore being developed as targets for cancer therapies. They are diverse not only in the messenger RNAs (mRNA) they target, but in thei...