- The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6
[作者：Zhang, H; Gao, ZQ; Wang, WJ; Liu, GF; Shtykova, EV; Xu, JH; Li, LF; Su, XD; Dong, YH,期刊：FEBS Letters, 页码：1147-1153 , 文章类型： Article，,卷期：2012年586-8]
- The COP9 signalosome (CSN) is a multiprotein complex containing eight subunits and is highly conserved from fungi to human. CSN is proposed to widely participate in many physiological processes, including protein degrada...
- A new function of ROD1 in nonsense-mediated mRNA decay
[作者：Brazao, TF; Demmers, J; van IJcken, W; Strouboulis, J; Fornerod, M; Romao, L; Grosveld, FG,期刊：FEBS Letters, 页码：1101-1110 , 文章类型： Article，,卷期：2012年586-8]
- RNA-binding proteins play a crucial role in the post-transcriptional regulation of gene expression. Polypyrimidine tract binding protein (PTB in humans) has been extensively characterized as an important splicing factor,...
- The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II
[作者：Lorenzen, I; Lokau, J; Dusterhoft, S; Trad, A; Garbers, C; Scheller, J; Rose-John, S; Grotzinger, J,期刊：FEBS Letters, 页码：1093-1100 , 文章类型： Article，,卷期：2012年586-8]
- A great number of physiological processes are regulated by the release of ectodomains of membrane proteins. A Disintegrin And Metalloprotease 17 (ADAM17) is one of the important enzymes, which mediate this process called...
- microRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-kappa B1 in murine macrophages
[作者：Qi, JN; Qiao, Y; Wang, P; Li, SQ; Zhao, W; Gao, CJ,期刊：FEBS Letters, 页码：1201-1207 , 文章类型： Article，,卷期：2012年586-8]
- Ligation of TLR4 with LPS in macrophages leads to the production of proinflammatory cytokines, which are central to eliminate viral and bacterial infection. However, uncontrolled TLR4 activation may contribute to pathoge...
- Biogenesis of Y RNA-derived small RNAs is independent of the microRNA pathway
[作者：Nicolas, FE; Hall, AE; Csorba, T; Turnbull, C; Dalmay, T,期刊：FEBS Letters, 页码：1226-1230 , 文章类型： Article，,卷期：2012年586-8]
- Y RNAs are approximately 100 nucleotide long conserved cytoplasmic non-coding RNAs, which produce smaller RNA fragments during apoptosis. Here we show that these smaller RNA molecules are also produced in non-stressed ce...
- Biophysical characterization of the isolated C-terminal region of the transient receptor potential vanilloid 1
[作者：Aguado-Llera, D; Bacarizo, J; Gregorio-Teruel, L; Taberner, FJ; Camara-Artigas, A; Neira, JL,期刊：FEBS Letters, 页码：1154-1159 , 文章类型： Article，,卷期：2012年586-8]
- Transient receptor potential (TRP) proteins are sensory-related cation channels. TRPV subfamily responds to vanilloids, generating a Ca2+ current. TRPV1, a thermal-sensitive non-selective ion channel, possesses six trans...
- Zebrafish p53 protein enhances the translation of its own mRNA in response to UV irradiation and CPT treatment
[作者：Zhao, XZ; Wu, N; Ding, LL; Liu, M; Liu, HZ; Lin, XK,期刊：FEBS Letters, 页码：1220-1225 , 文章类型： Article，,卷期：2012年586-8]
- p53 protein is an important regulatory factor involved in cell growth and development. In our previous study, we demonstrated that recombined zebrafish p53 protein could specifically bind to its own mRNA in vitro. To det...
- Cell density-dependent acetylation of Delta Np63 alpha is associated with p53-dependent cell cycle arrest
[作者：Chae, YS; Kim, H; Kim, D; Lee, H; Lee, HO,期刊：FEBS Letters, 页码：1128-1134 , 文章类型： Article，,卷期：2012年586-8]
- Delta Np63 alpha is a p63 isoform that is predominantly expressed in the epidermal stem cells and in cancer. To find the regulatory pathways of Delta Np63 alpha, we assessed whether Delta Np63 alpha is acetylated and det...
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