- Insights into ubiquitin-conjugating enzyme/co-activator interactions from the structure of the Pex4p:Pex22p complex
[作者：Williams, C; van den Berg, M; Panjikar, S; Stanley, WA; Distel, B; Wilmanns, M,期刊：EMBO journal, 页码：391-402 , 文章类型： Article，,卷期：2012年31-2]
- Ubiquitin-conjugating enzymes (E2s) coordinate distinct types of ubiquitination via specific E3 ligases, to a large number of protein substrates. While many E2 enzymes need only the presence of an E3 ligase for substrate...
- Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest
[作者：Liang, HQ; Lim, HH; Venkitaraman, A; Surana, U,期刊：EMBO journal, 页码：403-416 , 文章类型： Article，,卷期：2012年31-2]
- The spindle assembly checkpoint (SAC), an evolutionarily conserved surveillance pathway, prevents chromosome segregation in response to conditions that disrupt the kinetochore-microtubule attachment. Removal of the check...
- Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function
[作者：Kakizawa, S; Yamazawa, T; Chen, YL; Ito, A; Murayama, T; Oyamada, H; Kurebayashi, N; Sato, O; Watanabe, M; Mori, N; Oguchi, K; Sakurai, T; Takeshima, H; Saito, N; Iino, M,期刊：EMBO journal, 页码：417-428 , 文章类型： Article，,卷期：2012年31-2]
- Mobilization of intracellular Ca2+ stores regulates a multitude of cellular functions, but the role of intracellular Ca2+ release via the ryanodine receptor (RyR) in the brain remains incompletely understood. We found th...
- Wnt1/beta catenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
[作者：Duan, JZ; Gherghe, C; Liu, DX; Hamlett, E; Srikantha, L; Rodgers, L; Regan, JN; Rojas, M; Willis, M; Leask, A; Majesky, M; Deb, A,期刊：EMBO journal, 页码：429-442 , 文章类型： Article，,卷期：2012年31-2]
- Wnts are required for cardiogenesis but the role of specific Wnts in cardiac repair remains unknown. In this report, we show that a dynamic Wnt1/beta catenin injury response activates the epicardium and cardiac fibroblas...
- LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs
[作者：Ruzzenente, B; Metodiev, MD; Wredenberg, A; Bratic, A; Park, CB; Camara, Y; Milenkovic, D; Zickermann, V; Wibom, R; Hultenby, K; Erdjument-Bromage, H; Tempst, P; Brandt, U; Stewart, JB; Gustafsson, CM; Larsson, NG,期刊：EMBO journal, 页码：443-456 , 文章类型： Article，,卷期：2012年31-2]
- Regulation of mtDNA expression is critical for maintaining cellular energy homeostasis and may, in principle, occur at many different levels. The leucine-rich pentatricopeptide repeat containing (LRPPRC) protein regulate...
- Palmitoylated TMX and calnexin target to the mitochondria-associated membrane
[作者：Lynes, EM; Bui, M; Yap, MC; Benson, MD; Schneider, B; Ellgaard, L; Berthiaume, LG; Simmen, T,期刊：EMBO journal, 页码：457-470 , 文章类型： Article，,卷期：2012年31-2]
- The mitochondria-associated membrane (MAM) is a domain of the endoplasmic reticulum (ER) that mediates the exchange of ions, lipids and metabolites between the ER and mitochondria. ER chaperones and oxidoreductases are c...
|