- Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat
[作者：Kung, LF; Pagant, S; Futai, E; D'Arcangelo, JG; Buchanan, R; Dittmar, JC; Reid, RJD; Rothstein, R; Hamamoto, S; Snapp, EL; Schekman, R; Miller, EA,期刊：EMBO journal, 页码：1014-1027 , 文章类型： Article，,卷期：2012年31-4]
- Vesicle budding from the endoplasmic reticulum (ER) employs a cycle of GTP binding and hydrolysis to regulate assembly of the COPII coat. We have identified a novel mutation (sec24-m11) in the cargo-binding subunit, Sec2...
- Rescue of tropomyosin deficiency in Drosophila and human cancer cells by synaptopodin reveals a role of tropomyosin alpha in RhoA stabilization
[作者：Wong, JS; Iorns, E; Rheault, MN; Ward, TM; Rashmi, P; Weber, U; Lippman, ME; Faul, C; Mlodzik, M; Mundel, P,期刊：EMBO journal, 页码：1028-1040 , 文章类型： Article，,卷期：2012年31-4]
- Tropomyosins are widespread actin-binding proteins that influence numerous cellular functions including actin dynamics, cell migration, tumour suppression, and Drosophila oocyte development. Synaptopodin is another actin...
- Minor pseudopilin self-assembly primes type II secretion pseudopilus elongation
[作者：Cisneros, DA; Bond, PJ; Pugsley, AP; Campos, M; Francetic, O,期刊：EMBO journal, 页码：1041-1053 , 文章类型： Article，,卷期：2012年31-4]
- In Gram-negative bacteria, type II secretion systems (T2SS) assemble inner membrane proteins of the major pseudopilin PulG (GspG) family into periplasmic filaments, which could drive protein secretion in a piston-like ma...
- The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation
[作者：von Eyss, B; Maaskola, J; Memczak, S; Mollmann, K; Schuetz, A; Loddenkemper, C; Tanh, MD; Otto, A; Muegge, K; Heinemann, U; Rajewsky, N; Ziebold, U,期刊：EMBO journal, 页码：972-985 , 文章类型： Article，,卷期：2012年31-4]
- for their dependence on the Retinoblastoma protein and their role in cellular proliferation. E2F3 is uniquely amplified in specific human tumours where its expression is inversely correlated with the survival of patients...
- Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development
[作者：Stadhouders, R; Thongjuea, S; Andrieu-Soler, C; Palstra, RJ; Bryne, JC; van den Heuvel, A; Stevens, M; de Boer, E; Kockx, C; van der Sloot, A; van den Hout, M; van IJcken, W; Eick, D; Lenhard, B; Grosveld, F; Soler, E,期刊：EMBO journal, 页码：986-999 , 文章类型： Article，,卷期：2012年31-4]
- The key haematopoietic regulator Myb is essential for coordinating proliferation and differentiation. ChIP-Sequencing and Chromosome Conformation Capture (3C)-Sequencing were used to characterize the structural and prote...
- How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly
[作者：Didry, D; Cantrelle, FX; Husson, C; Roblin, P; Moorthy, AME; Perez, J; Le Clainche, C; Hertzog, M; Guittet, E; Carlier, MF; van Heijenoort, C; Renault, L,期刊：EMBO journal, 页码：1000-1013 , 文章类型： Article，,卷期：2012年31-4]
- beta-Thymosin (beta T) and WH2 domains are widespread, intrinsically disordered actin-binding peptides that display significant sequence variability and different regulations of actin self-assembly in motile and morphoge...
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