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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共25条记录   The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring [作者：Akopian, T; Kandror, O; Raju, RM; UnniKrishnan, M; Rubin, EJ; Goldberg, AL,期刊：EMBO journal, 页码：1529-1541 , 文章类型： Article，,卷期：2012年31-6] Mycobacterium tuberculosis (Mtb) contains two clpP genes, both of which are essential for viability. We expressed and purified Mtb ClpP1 and ClpP2 separately. Although each formed a tetradecameric structure and was proce... Soj/ParA stalls DNA replication by inhibiting helix formation of the initiator protein DnaA [作者：Scholefield, G; Errington, J; Murray, H,期刊：EMBO journal, 页码：1542-1555 , 文章类型： Article，,卷期：2012年31-6] Control of DNA replication initiation is essential for normal cell growth. A unifying characteristic of DNA replication initiator proteins across the kingdoms of life is their distinctive AAA + nucleotide-binding domains... Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation [作者：Beattie, TR; Bell, SD,期刊：EMBO journal, 页码：1556-1567 , 文章类型： Article，,卷期：2012年31-6] Chromosomal DNA replication requires one daughter strand-the lagging strand-to be synthesised as a series of discontinuous, RNA-primed Okazaki fragments, which must subsequently be matured into a single covalent DNA stra... Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex [作者：Saikrishnan, K; Yeeles, JT; Gilhooly, NS; Krajewski, WW; Dillingham, MS; Wigley, DB,期刊：EMBO journal, 页码：1568-1578 , 文章类型： Article，,卷期：2012年31-6] In bacterial cells, processing of double-stranded DNA breaks for repair by homologous recombination is dependent upon the recombination hotspot sequence Chi and is catalysed by either an AddAB-or RecBCD-type helicase-nuc... Structure and assembly of the SF3a splicing factor complex of U2 snRNP [作者：Lin, PC; Xu, RM,期刊：EMBO journal, 页码：1579-1590 , 文章类型： Article，,卷期：2012年31-6] SF3a is an evolutionarily conserved heterotrimeric complex essential for pre-mRNA splicing. It functions in spliceosome assembly within the mature U2 snRNP (small nuclear ribonucleoprotein particle), and its displacement... Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre [作者：Rasche, N; Dybkov, O; Schmitzova, J; Akyildiz, B; Fabrizio, P; Luhrmann, R,期刊：EMBO journal, 页码：1591-1604 , 文章类型： Article，,卷期：2012年31-6] RNA-structural elements play key roles in pre-mRNA splicing catalysis; yet, the formation of catalytically competent RNA structures requires the assistance of spliceosomal proteins. We show that the S. cerevisiae Cwc2 pr... Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor [作者：Pena, A; Gewartowski, K; Mroczek, S; Cuellar, J; Szykowska, A; Prokop, A; Czarnocki-Cieciura, M; Piwowarski, J; Tous, C; Aguilera, A; Carrascosa, JL; Valpuesta, JM; Dziembowski, A,期刊：EMBO journal, 页码：1605-1616 , 文章类型： Article，,卷期：2012年31-6] The THO complex is a key factor in co-transcriptional formation of export-competent messenger ribonucleoprotein particles, yet its structure and mechanism of chromatin recruitment remain unknown. In yeast, this complex h... Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1 (vol 30, pg 3019, 2011) [作者：Robinson, JLL; MacArthur, S; Ross-Innes, CS; Tilley, WD; Neal, DE; Mills, IG; Carroll, JS,期刊：EMBO journal, 页码：1617-1617 , 文章类型： Correction，,卷期：2012年31-6] Hypoxia regulates glutamate receptor trafficking through an HIF-independent mechanism (vol 31, pg 1379, 2012) [作者：Park, EC; Ghose, P; Shao, ZY; Ye, Q; Kang, LJ; Xu, XZS; Powell-Coffman, JA; Rongo, C,期刊：EMBO journal, 页码：1618-1619 , 文章类型： Correction，,卷期：2012年31-6]